PI3K/AKT signaling pathway as a critical regulator of epithelial-mesenchymal transition in colorectal tumor cells

A Maharati, M Moghbeli - Cell Communication and Signaling, 2023 - Springer
Colorectal cancer (CRC) is one of the most frequent gastrointestinal malignancies that are
considered as a global health challenge. Despite many progresses in therapeutic methods …

PI3K/AKT signaling pathway as a critical regulator of Cisplatin response in tumor cells

ZN Navaei, G Khalili-Tanha, AS Zangouei… - Oncology …, 2022 - pmc.ncbi.nlm.nih.gov
Chemotherapy is one of the main therapeutic modalities for cancer patients. Cisplatin
(CDDP), as one of the first-line drugs, is of great importance in the chemotherapy of various …

Long non-coding RNAs as the critical regulators of epithelial mesenchymal transition in colorectal tumor cells: an overview

AA Hamidi, G Khalili-Tanha, Z Nasrpour Navaei… - Cancer cell …, 2022 - Springer
Colorectal cancer (CRC) is the second most common cause of cancer mortality and a major
health challenge worldwide. Despite advances in therapeutic and diagnostic methods, there …

Ovarian cancer stem cells and targeted therapy

V Keyvani, M Farshchian, SA Esmaeili, H Yari… - Journal of ovarian …, 2019 - Springer
Background Ovarian cancer has the highest ratio of mortality among gynecologic
malignancies. Chemotherapy is one of the most common treatment options for ovarian …

MicroRNAs as the critical regulators of Cisplatin resistance in ovarian cancer cells

M Moghbeli - Journal of ovarian research, 2021 - Springer
Background Ovarian cancer (OC) is one of the leading causes of cancer related deaths
among women. Due to the asymptomatic tumor progression and lack of efficient screening …

MicroRNAs as the critical regulators of cell migration and invasion in thyroid cancer

AA Hamidi, N Taghehchian, Z Basirat, AS Zangouei… - Biomarker …, 2022 - Springer
Thyroid cancer (TC) is one of the most frequent endocrine malignancies that is more
common among females. Tumor recurrence is one of the most important clinical …

Molecular mechanisms of the microRNA-132 during tumor progressions

M Moghbeli, AS Zangouei, Z Nasrpour Navaii… - Cancer Cell …, 2021 - Springer
Cancer as one of the leading causes of human deaths has always been one of the main
health challenges in the world. Despite recent advances in therapeutic and diagnostic …

MicroRNAs as the critical regulators of Doxorubicin resistance in breast tumor cells

AS Zangouei, M Alimardani, M Moghbeli - Cancer Cell International, 2021 - Springer
Background Chemotherapy is one of the most common treatment options for breast cancer
(BC) patients. However, about half of the BC patients are chemotherapeutic resistant …

MYH9 is a novel cancer stem cell marker and prognostic indicator in esophageal cancer that promotes oncogenesis through the PI3K/AKT/mTOR axis

JD Kai, LH Cheng, BF Li, K Kang, F Xiong… - Cell biology …, 2022 - Wiley Online Library
MYH9 encodes the heavy chain of nonmuscle myosin IIA, a ubiquitously expressed
cytoplasmic myosin that regulates the actin cytoskeleton, cell migration, cell polarization …

MicroRNAs as the pivotal regulators of cisplatin resistance in head and neck cancers

F Tolue Ghasaban, A Maharati, AS Zangouei… - Cancer cell …, 2023 - Springer
Although, there is a high rate of good prognosis in early stage head and neck tumors, about
half of these tumors are detected in advanced stages with poor prognosis. A combination of …