Metabolomics, the comprehensive measurement of low-molecular-weight molecules in
biological fluids used for metabolic phenotyping, has emerged as a promising tool to better …

The role of the host microbiome has come to the forefront as a potential modulator of cancer
metabolism and could be a future target for precision medicine. A recent study revealed that …

The functional interactions between the gut microbiota and the host are important for host
physiology, homeostasis, and sustained health. We compared the skeletal muscle of germ …

Rates of colon cancer are much higher in African Americans (65: 100,000) than in rural
South Africans (< 5: 100,000). The higher rates are associated with higher animal protein …

Metabolic profiling of biological samples provides important insights into multiple
physiological and pathological processes but is hindered by a lack of automated annotation …

Aims To characterize serum metabolic signatures associated with atherosclerosis in the
coronary or carotid arteries and subsequently their association with incident cardiovascular …

Obesity is a major public health problem worldwide. We used 24-hour urinary metabolic
profiling by proton (1H) nuclear magnetic resonance (NMR) spectroscopy and ion exchange …

To gain insight into the complex microbiome-gut-brain axis in irritable bowel syndrome (IBS),
several modalities of biological and clinical data must be combined. We aimed to identify …

Background Immune-mediated inflammatory diseases (IMIDs) are a group of complex and
prevalent diseases where disease diagnostic and activity monitoring is highly challenging …

ABSTRACT Background Alaska Native (AN) people have the world's highest recorded
incidence of sporadic colorectal cancer (CRC)(∼ 91: 100,000), whereas rural African (RA) …