Iron is an essential micronutrient for virtually all living cells. In infectious diseases, both
invading pathogens and mammalian cells including those of the immune system require iron …

Macrophages are cells of the innate immunity constituting the mononuclear phagocyte
system and endowed with remarkable different roles essential for defense mechanisms …

Improvements in the control of haemorrhage after trauma have resulted in the survival of
many people who would otherwise have died from the initial loss of blood. However, the …

Iron is an essential nutrient for both humans and pathogenic microbes. Because of its ability
to exist in one of two oxidation states, iron is an ideal redox catalyst for diverse cellular …

The immune system protects from infections primarily by detecting and eliminating the
invading pathogens; however, the host organism can also protect itself from infectious …

“Asymptomatic” Malaria: A Chronic and Debilitating Infection That Should Be Treated | PLOS
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Invasive strains of non-typhoidal salmonellae have emerged as a prominent cause of
bloodstream infection in African adults and children, with an associated case fatality of 20 …

The immune system probably evolved to limit the negative effects exerted by pathogens on
host homeostasis. This defence strategy relies on the concerted action of innate and …

Our goal is to present recent progress in understanding the biological mechanisms
underlying anemia from a public health perspective. We describe important advances in …

Iron lies at the center of a battle for nutritional resource between higher organisms and their
microbial pathogens. The iron status of the human host affects the pathogenicity of …