Cognitive and behavioural flexibility permit the appropriate adjustment of thoughts and
behaviours in response to changing environmental demands. Brain mechanisms enabling …

Working memory is the cognitive system in charge of the temporary maintenance of
information in view of its on-going processing. Lying at the centre of cognition, it has become …

The superior frontal gyrus (SFG) is located at the superior part of the prefrontal cortex and is
involved in a variety of functions, suggesting the existence of functional subregions …

Previously we showed that working memory training decreased the discounting of future
rewards in stimulant addicts without affecting a go/no-go task. While a relationship between …

The human prefrontal cortex contains two prominent areas, the frontal eye field and the
inferior frontal junction, that are crucially involved in the orchestrating functions of attention …

Cognitive flexibility involves dynamic processes that allow adaptation of our thinking and
behavior in response to changing contextual demands. Despite a large consensus about its …

The insula cortex and hypothalamus are implicated in eating behaviour, and contain
receptor sites for peptides and hormones controlling energy balance. The insula …

Working memory (WM) is a latent cognitive structure that serves to store and manipulate a
limited amount of information over a short time period. How information is maintained in WM …

Normal aging is characterized by brain glucose metabolism decline predominantly in the
prefrontal cortex. The goal of the present study was to assess whether this change was …

Background: Apathy is associated with reduced antidepressant response and dementia in
late-life depression (LLD). However, the functional cerebral basis of apathy is understudied …