In vivo electrochemical sensing based on implantable microelectrodes is a strong driving
force of analytical neurochemistry in brain. The complex and dynamic neurochemical …

Secondary injury is a term applied to the destructive and self-propagating biological
changes in cells and tissues that lead to their dysfunction or death over hours to weeks after …

Extracellular glutamate of glial origin modulates glial and neuronal glutamate release and
synaptic plasticity. Estimates of the tonic basal concentration of extracellular glutamate …

It is extremely challenging to chemically diagnose disorders of the brain. There is hence
great interest in designing and optimizing tools for direct detection of chemical biomarkers …

Excitotoxicity is likely to occur in pathological scenarios in which mitochondrial function is
already compromised, shaping neuronal responses to glutamate. In fact, mitochondria …

The ever-increasing daily use of engineered nanoparticles will lead to heightened levels of
these materials in the environment. These nanomaterials will eventually go into the …

Ammonium is a preferred source of nitrogen for plants but is toxic at high levels. Plant
ammonium transporters (AMTs) play an essential role in NH4+ uptake, but the mechanism …

We report the semisynthesis of a fluorescent glutamate sensor protein on cell surfaces.
Sensor excitation at 547 nm yields a glutamate-dependent emission spectrum between 550 …

A screen printed carbon electrode (SPCE) containing the electrocatalyst Meldola's Blue
(MB) has been investigated as the base transducer for a reagentless glutamate biosensor …

Glutamate, a major excitatory neurotransmitter in the central nervous system, is essential for
regulation of thought, movement, memory, and other higher functions controlled by the brain …