The molecular structure of cell adhesion molecules

C Chothia, EY Jones - Annual review of biochemistry, 1997 - annualreviews.org
Considerable advances have been made in our knowledge of the molecular structure of cell
adhesion molecules, their binding sites, and adhesion complexes. For the cadherins, protein …

Distribution and possible roles of the highly polysialylated neural cell adhesion molecule (NCAM-H) in the developing and adult central nervous system

T Seki, Y Arai - Neuroscience research, 1993 - Elsevier
The neural cell adhesion molecule (NCAM) is a cell surface glycoprotein which is thought to
mediate cell adhesion and recognition. During developmental stages, NCAM is highly …

Impact of sedentarism due to the COVID-19 home confinement on neuromuscular, cardiovascular and metabolic health: Physiological and pathophysiological …

M Narici, GD Vito, M Franchi, A Paoli… - European journal of …, 2021 - Taylor & Francis
The COVID-19 pandemic is an unprecedented health crisis as entire populations have been
asked to self-isolate and live in home-confinement for several weeks to months, which in …

An autosomal transcript in skeletal muscle with homology to dystrophin

DR Love, DF Hill, G Dickson, NK Spurr, BC Byth… - Nature, 1989 - nature.com
THE Duchenne muscular dystrophy (DMD) gene has been localized to chromosome Xp211–
6 and codes for a 14-kilobase (kb) transcript7 and a protein called dystrophin8, of relative …

Human carcinoembryonic antigen functions as a general inhibitor of anoikis

C Ordoñez, RA Screaton, C Ilantzis, CP Stanners - Cancer research, 2000 - AACR
Human carcinoembryonic antigen (CEA), a widely used tumor marker, and CEACAM6
[formerly nonspecific cross-reacting antigen (NCA)] are up-regulated in many types of …

N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signalling

U Cavallaro, J Niedermeyer, M Fuxa, G Christofori - Nature cell biology, 2001 - nature.com
Loss of expression of neural cell-adhesion molecule (N-CAM) is implicated in the
progression of tumour metastasis. Here we show that N-CAM modulates neurite outgrowth …

Long-term high-level exercise promotes muscle reinnervation with age

S Mosole, U Carraro, H Kern, S Loefler… - … of Neuropathology & …, 2014 - academic.oup.com
The histologic features of aging muscle suggest that denervation contributes to atrophy, that
immobility accelerates the process, and that routine exercise may protect against loss of …

Zippers make signals: NCAM-mediated molecular interactions and signal transduction

PS Walmod, K Kolkova, V Berezin, E Bock - Neurochemical research, 2004 - Springer
The neural cell adhesion molecule, NCAM, is involved in multiple cis-and trans-homophilic
interactions (NCAM binding to NCAM) thereby facilitating cell–cell adhesion through the …

Mammalian target of rapamycin (mTOR) signaling at the crossroad of muscle fiber fate in sarcopenia

G Sirago, A Picca, R Calvani, HJ Coelho-Júnior… - International Journal of …, 2022 - mdpi.com
The mammalian target of rapamycin (mTOR) is a major regulator of skeletal myocyte
viability. The signaling pathways triggered by mTOR vary according to the type of …

Neurite outgrowth in response to transfected N-CAM changes during development and is modulated by polysialic acid

P Doherty, J Cohen, FS Walsh - Neuron, 1990 - cell.com
We have used monolayers of control 3T3 cells and 3T3 cells transfected with a cDNA
encoding human N-CAM as a culture substrate for embryonic chick retinal ganglion cells …