As one of the most common metastatic sites of malignancies, bone has a unique
microenvironment that allows metastatic tumor cells to grow and flourish. The fenestrated …

The chemotactic cytokines, or chemokines, comprise a superfamily of polypeptides with a
wide range of activities that include recruitment of immune cells to sites of infection and …

Head and neck squamous cell carcinomas (HNSCCs) are aggressive diseases with a
dismal patient prognosis. Despite significant advances in treatment modalities, the five-year …

Background: The molecular mechanisms involved in the invasion of bone by oral squamous
cell carcinomas (OSCC) are poorly understood, and little is known about the role of cancer …

Hepatocellular carcinoma (HCC) is a prevalent malignant tumor worldwide, with an
unsatisfactory prognosis, although treatments are improving. One of the main challenges for …

Chemokine receptors have a crucial role in the development and progression of lymphoid
neoplasms. To determine the chemokine receptor expression profile in gastric mucosa …

Human papillomaviruses (HPVs) cause cancers of the uterine cervix, oropharynx, anus, and
vulvovaginal tract. Low-risk HPVs, such as HPV6 and 11, can also cause benign mucosal …

Molecular characteristics of carcinoma arising from mature cystic teratoma of the ovary
(MCT) remain unclear due to its rarity. We analyzed RNA-sequencing data of 2322 pan …

The topoisomerase I (TOP1) inhibitor irinotecan triggers cell death by trapping TOP1 on
DNA, generating cytotoxic protein-linked DNA breaks (PDBs). Despite its wide application in …

Chemokine receptor-ligand interactions are important to support functioning of both normal
and pathologic cells. The expression and function of chemokine receptors in epithelial …