Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments

SN Lone, S Nisar, T Masoodi, M Singh, A Rizwan… - Molecular cancer, 2022 - Springer
Over the past decade, invasive techniques for diagnosing and monitoring cancers are slowly
being replaced by non-invasive methods such as liquid biopsy. Liquid biopsies have …

Exosome-based immunotherapy: a promising approach for cancer treatment

Z Xu, S Zeng, Z Gong, Y Yan - Molecular cancer, 2020 - Springer
In the era of the rapid development of cancer immunotherapy, there is a high level of interest
in the application of cell-released small vesicles that stimulate the immune system. As cell …

Extracellular vesicles and particles impact the systemic landscape of cancer

S Lucotti, CM Kenific, H Zhang, D Lyden - The EMBO journal, 2022 - embopress.org
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

miRNAs in lung cancer. A systematic review identifies predictive and prognostic miRNA candidates for precision medicine in lung cancer

S Zhong, H Golpon, P Zardo, J Borlak - Translational Research, 2021 - Elsevier
Lung cancer (LC) is the leading cause of cancer-related death worldwide and miRNAs play
a key role in LC development. To better diagnose LC and to predict drug treatment …

Extracellular vesicles in liquid biopsies as biomarkers for solid tumors

B Irmer, S Chandrabalan, L Maas, A Bleckmann… - Cancers, 2023 - mdpi.com
Simple Summary During the past decade, liquid biopsy-related publications have increased
exponentially, demonstrating the great potential of screening body fluids for diagnosis …

Roles of exosomes in immunotherapy for solid cancers

C Lyu, H Sun, Z Sun, Y Liu, Q Wang - Cell Death & Disease, 2024 - nature.com
Although immunotherapy has made breakthrough progress, its efficacy in solid tumours
remains unsatisfactory. Exosomes are the main type of extracellular vesicles that can deliver …

Circulating extracellular vesicles are effective biomarkers for predicting response to cancer therapy

E Zhou, Y Li, F Wu, M Guo, J Xu, S Wang, Q Tan… - …, 2021 - thelancet.com
Cancer remains one of the most challenging diseases, as many patients show limited
therapeutic response to treatment. Liquid biopsy is a minimally invasive method that has the …

[HTML][HTML] Exosome regulation of immune response mechanism: Pros and cons in immunotherapy

JM Essola, M Zhang, H Yang, F Li, B Xia… - Bioactive Materials, 2024 - Elsevier
Due to its multiple features, including the ability to orchestrate remote communication
between different tissues, the exosomes are the extracellular vesicles arousing the highest …

Non‐coding RNAs in cancer immunotherapy: Predictive biomarkers and targets

M Alahdal, E Elkord - Clinical and translational medicine, 2023 - Wiley Online Library
Background To date, standardising clinical predictive biomarkers for assessing the response
to immunotherapy remains challenging due to variations in personal genetic signatures …

Epigenetic mechanisms of resistance to immune checkpoint inhibitors

A Perrier, A Didelot, P Laurent-Puig, H Blons, S Garinet - Biomolecules, 2020 - mdpi.com
Immune checkpoint inhibitors (ICIs) have demonstrated to be highly efficient in treating solid
tumors; however, many patients have limited benefits in terms of response and survival. This …