Neutrophils in tuberculosis: Cell biology, cellular networking and multitasking in host defense

RR Borkute, S Woelke, G Pei, A Dorhoi - International journal of molecular …, 2021 - mdpi.com
Neutrophils readily infiltrate infection foci, phagocytose and usually destroy microbes. In
tuberculosis (TB), a chronic pulmonary infection caused by Mycobacterium tuberculosis …

Susceptibility of white-tailed deer (Odocoileus virginianus) to SARS-CoV-2

MV Palmer, M Martins, S Falkenberg, A Buckley… - Journal of …, 2021 - Am Soc Microbiol
The origin of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus
causing the global coronavirus disease 2019 (COVID-19) pandemic, remains a mystery …

Comparative pathology of experimental pulmonary tuberculosis in animal models

L Hunter, I Ruedas-Torres, I Agulló-Ros… - Frontiers in Veterinary …, 2023 - frontiersin.org
Research in human tuberculosis (TB) is limited by the availability of human tissues from
patients, which is often altered by therapy and treatment. Thus, the use of animal models is a …

Intestinal single-cell atlas reveals novel lymphocytes in pigs with similarities to human cells

JE Wiarda, JM Trachsel… - Life science …, 2022 - life-science-alliance.org
Lymphocytes can heavily influence intestinal health, but resolving intestinal lymphocyte
function is challenging as the intestine contains a vastly heterogeneous mixture of cells. Pigs …

Early dynamics of innate immunity during pulmonary tuberculosis

B Corleis, A Dorhoi - Immunology letters, 2020 - Elsevier
Tuberculosis (TB) most frequently affects the lung, with Mycobacterium tuberculosis (Mtb),
the etiologic agent of TB, promptly gaining access to lung-resident myeloid cells, notably …

The bovine tuberculoid granuloma

MV Palmer, C Kanipe, PM Boggiatto - Pathogens, 2022 - mdpi.com
The bovine tuberculoid granuloma is the hallmark lesion of bovine tuberculosis (bTB) due to
Mycobacterium bovis infection. The pathogenesis of bTB, and thereby the process of bovine …

Mycobacterial Infection of Precision-Cut Lung Slices Reveals Type 1 Interferon Pathway Is Locally Induced by Mycobacterium bovis but Not M. tuberculosis in a …

A Remot, F Carreras, A Coupé… - Frontiers in veterinary …, 2021 - frontiersin.org
Tuberculosis exacts a terrible toll on human and animal health. While Mycobacterium
tuberculosis (Mtb) is restricted to humans, Mycobacterium bovis (Mb) is present in a large …

Integrative genomics of the mammalian alveolar macrophage response to intracellular mycobacteria

TJ Hall, MP Mullen, GP McHugo, KE Killick, SC Ring… - BMC genomics, 2021 - Springer
Abstract Background Bovine TB (bTB), caused by infection with Mycobacterium bovis, is a
major endemic disease affecting global cattle production. The key innate immune cell that …

Methods in isolation and characterization of bovine monocytes and macrophages

F Ceciliani, GÁ Morales, G De Matteis, F Grandoni… - Methods, 2021 - Elsevier
Monocytes and macrophages belong to the mononuclear phagocyte system and play
important roles in both physiological and pathological processes. The cells belonging to the …

VapC12 ribonuclease toxin modulates host immune response during Mycobacterium tuberculosis infection

S Tyagi, S Sadhu, T Sharma, A Paul… - Frontiers in …, 2024 - frontiersin.org
Mechanistic understanding of antibiotic persistence is a prerequisite in controlling the
emergence of MDR cases in Tuberculosis (TB). We have reported that the cholesterol …