Considerations for the use of phage therapy in clinical practice

GA Suh, TP Lodise, PD Tamma… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Increasing antimicrobial resistance and medical device-related infections have led to a
renewed interest in phage therapy as an alternative or adjunct to conventional …

Shopping for phages? Unpacking design rules for therapeutic phage cocktails

C Lood, PJ Haas, V van Noort, R Lavigne - Current Opinion in Virology, 2022 - Elsevier
In bacteriophage therapy, the combination of different phages into a single cocktail is of
critical importance to overcome the narrow host range of single phage isolates. Today, the …

High throughput platform technology for rapid target identification in personalized phage therapy

F Bayat, A Hilal, M Thirugnanasampanthar… - Nature …, 2024 - nature.com
As bacteriophages continue to gain regulatory approval for personalized human therapy
against antibiotic-resistant infections, there is a need for transformative technologies for …

Analysis of bacteriophage behavior of a human RNA virus, SARS-CoV-2, through the integrated approach of immunofluorescence microscopy, proteomics and D …

C Brogna, V Costanzo, B Brogna, DR Bisaccia… - International Journal of …, 2023 - mdpi.com
SARS-CoV-2, one of the human RNA viruses, is widely studied around the world. Significant
efforts have been made to understand its molecular mechanisms of action and how it …

Monitoring phage-induced lysis of gram-negatives in real time using a fluorescent DNA dye

JE Egido, C Toner-Bartelds, AR Costa, SJJ Brouns… - Scientific Reports, 2023 - nature.com
Bacteriophages (phages) are viruses that specifically attack bacteria. Their use as
therapeutics, which constitutes a promising alternative to antibiotics, heavily relies on …

Bacteriophages Combined With Subtherapeutic Doses of Flucloxacillin Act Synergistically Against Staphylococcus aureus Experimental Infective Endocarditis

J Save, YA Que, JM Entenza, C Kolenda… - Journal of the …, 2022 - Am Heart Assoc
Background The potential of phage therapy for the treatment of endovascular
Staphylococcus aureus infections remains to be evaluated. Methods and Results The …

[HTML][HTML] Isolation and characterization of lytic bacteriophages from sewage at an egyptian tertiary care hospital against methicillin-resistant Staphylococcus aureus …

S Samir, A El-Far, H Okasha, R Mahdy, F Samir… - Saudi Journal of …, 2022 - Elsevier
Abstract Background Methicillin resistant Staphylococcus aureus (MRSA) is a pathogen to
humans causing life-threatening infections. MRSA have the capability to grow resistance to …

Commercial bacteriophage preparations for the control of Listeria monocytogenes and Shiga toxin-producing Escherichia coli in raw and pasteurized milk

E Everhart, S Carson, K Atkinson, DJ D'Amico - Food Microbiology, 2025 - Elsevier
Listeria monocytogenes was the etiologic agent in nearly all recent outbreaks in North
America attributed to pasteurized dairy products, whereas Escherichia coli O157 infections …

Development of TaqMan Real-Time PCR Protocols for Simultaneous Detection and Quantification of the Bacterial Pathogen Ralstonia solanacearum and Their …

E Bertolini, À Figàs-Segura, B Álvarez, EG Biosca - Viruses, 2023 - mdpi.com
Ralstonia solanacearum is the causal agent of bacterial wilt, one of the most destructive
diseases of solanaceous plants, affecting staple crops worldwide. The bacterium survives in …

Multiparametric sensing of outer membrane vesicle-derived supported lipid bilayers demonstrates the specificity of bacteriophage interactions

K Bali, R McCoy, Z Lu, J Treiber, A Savva… - ACS Biomaterials …, 2023 - ACS Publications
The use of bacteriophages, viruses that specifically infect bacteria, as antibiotics has
become an area of great interest in recent years as the effectiveness of conventional …