Upon receipt in the dorsal horn (DH) of the spinal cord, nociceptive (pain-signalling)
information from the viscera, skin and other organs is subject to extensive processing by a …

Memory is essential to adaptive behavior because it allows past experience to guide
choices. Emerging findings indicate that the neurotransmitter dopamine, which signals …

Fear is an adaptive component of the acute “stress” response to potentially-dangerous
(external and internal) stimuli which threaten to perturb homeostasis. However, when …

The dopaminergic system plays a pivotal role in the central nervous system via its five
diverse receptors (D1–D5). Dysfunction of dopaminergic system is implicated in many …

Dopamine is an important neurotransmitter that plays a key role in neuropsychiatric illness.
Sex differences in dopaminergic signaling have been acknowledged for decades and have …

It is only recently that a number of studies on synaptic plasticity in the hippocampus and
other brain areas have considered that a heterosynaptic modulatory input could be recruited …

Substantial evidence indicates that the lateral septum (LS) plays a critical role in regulating
processes related to mood and motivation. This review presents findings from the basic …

Dopamine (DA) and DA receptors (DR) have been extensively studied in the central nervous
system (CNS), but their role in the periphery is still poorly understood. Here we summarize …

Recent insights have demonstrated a central role for dopaminergic neurotransmission in
modulating pain perception and natural analgesia within supraspinal regions, including the …

Ambient ionization methods for MS enable direct, high-throughput measurements of
samples in the open air. Here, we report on one such method, desorption electrospray …