Precision control of CRISPR-Cas9 using small molecules and light
The CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system is an
adaptive immune system of bacteria that has furnished several RNA-guided DNA …
adaptive immune system of bacteria that has furnished several RNA-guided DNA …
Recent advances in genome-editing technology with CRISPR/Cas9 variants and stimuli-responsive targeting approaches within tumor cells: a future perspective of …
The innovative advances in transforming clustered regularly interspaced short palindromic
repeats-associated protein 9 (CRISPR/Cas9) into different variants have taken the art of …
repeats-associated protein 9 (CRISPR/Cas9) into different variants have taken the art of …
ICEberg 2.0: an updated database of bacterial integrative and conjugative elements
M Liu, X Li, Y Xie, D Bi, J Sun, J Li, C Tai… - Nucleic acids …, 2019 - academic.oup.com
Abstract ICEberg 2.0 (http://db-mml. sjtu. edu. cn/ICEberg/) is an updated database that
provides comprehensive information about bacterial integrative and conjugative elements …
provides comprehensive information about bacterial integrative and conjugative elements …
AcrPred: A hybrid optimization with enumerated machine learning algorithm to predict Anti-CRISPR proteins
CRISPR-Cas, as a tool for gene editing, has received extensive attention in recent years.
Anti-CRISPR (Acr) proteins can inactivate the CRISPR-Cas defense system during …
Anti-CRISPR (Acr) proteins can inactivate the CRISPR-Cas defense system during …
Galaxy and Apollo as a biologist-friendly interface for high-quality cooperative phage genome annotation
In the modern genomic era, scientists without extensive bioinformatic training need to apply
high-power computational analyses to critical tasks like phage genome annotation. At the …
high-power computational analyses to critical tasks like phage genome annotation. At the …
PhageScope: a well-annotated bacteriophage database with automatic analyses and visualizations
Bacteriophages are viruses that infect bacteria or archaea. Understanding the diverse and
intricate genomic architectures of phages is essential to study microbial ecosystems and …
intricate genomic architectures of phages is essential to study microbial ecosystems and …
CRISPR-Cas systems restrict horizontal gene transfer in Pseudomonas aeruginosa
RM Wheatley, RC MacLean - The ISME journal, 2021 - academic.oup.com
CRISPR-Cas systems provide bacteria and archaea with an adaptive immune system that
targets foreign DNA. However, the xenogenic nature of immunity provided by CRISPR-Cas …
targets foreign DNA. However, the xenogenic nature of immunity provided by CRISPR-Cas …
dbAPIS: a database of a nti-p rokaryotic i mmune s ystem genes
Anti-prokaryotic immune system (APIS) proteins, typically encoded by phages, prophages,
and plasmids, inhibit prokaryotic immune systems (eg restriction modification, toxin-antitoxin …
and plasmids, inhibit prokaryotic immune systems (eg restriction modification, toxin-antitoxin …
Machine-learning approach expands the repertoire of anti-CRISPR protein families
The CRISPR-Cas are adaptive bacterial and archaeal immunity systems that have been
harnessed for the development of powerful genome editing and engineering tools. In the …
harnessed for the development of powerful genome editing and engineering tools. In the …
A unified resource for tracking anti-CRISPR names
Dear editors In the battle between CRISPR-Cas* prokaryotic immune systems and the
elements that they target, a diverse array of ''anti-CRISPR''proteins have evolved. These …
elements that they target, a diverse array of ''anti-CRISPR''proteins have evolved. These …