The estimation of power in two-level models used to analyze data that are hierarchically
structured is particularly complex because the outcome contains variance at two levels that …

Background Interventions need to be developed prior to the feasibility and piloting phase of
a study. There are a variety of published approaches to developing interventions …

Background Numerous models, frameworks, and theories exist for specific aspects of
implementation research, including for determinants, strategies, and outcomes. However …

Digital health interventions have enormous potential as scalable tools to improve health and
healthcare delivery by improving effectiveness, efficiency, accessibility, safety, and …

Environmental concerns arising from the release of greenhouse gases have stimulated the
search for more sustainable technologies, including bioethanol production from …

En este trabajo se elabora un marco conceptual y se desarrollan unos principios básicos
para fundamentar un sistema de clasificación de los diseños de investigación más usuales …

The wide variety of dissemination and implementation designs now being used to evaluate
and improve health systems and outcomes warrants review of the scope, features, and …

To build a coherent knowledge base about what psychological intervention strategies work,
develop interventions that have positive societal impact, and maintain and increase this …

Background An understanding of the individual and combined effects of a set of intervention
components is important for moving the science of preventive medicine interventions …

Abstract Background In 2015, Collins and Varmus articulated a vision for precision medicine
emphasizing molecular characterization of illness to identify actionable biomarkers to …