Pharmacological activities of natural triterpenoids and their therapeutic implications

P Dzubak, M Hajduch, D Vydra, A Hustova… - Natural product …, 2006 - pubs.rsc.org
Covering: 1990–2005. Previous review: Nat. Prod. Rep., 2005, 22, 487 This article reviews
the pharmacological activity of naturally occurring triterpenoids excluding the degraded …

Pharmacological properties of the ubiquitous natural product betulin

S Alakurtti, T Mäkelä, S Koskimies… - European journal of …, 2006 - Elsevier
Betulin (lup-20 (29)-ene-3β, 28-diol) is an abundant naturally occurring triterpene and it is
found predominantly in bushes and trees forming the principal extractive (up to 30% of dry …

Betulinic acid for cancer treatment and prevention

S Fulda - International journal of molecular sciences, 2008 - mdpi.com
Betulinic acid is a natural product with a range of biological effects, for example potent
antitumor activity. This anticancer property is linked to its ability to induce apoptotic cell …

Birch bark research and development

PA Krasutsky - Natural product reports, 2006 - pubs.rsc.org
Covering: 1995 to 2006 This review will detail progress made in the previous decade on the
chemistry and bioactivity of birch bark extractive products. Current and future applications of …

[PDF][PDF] Бетулин и его производные. Химия и биологическая активность

ГА Толстиков, ОБ Флехтер, ЭЭ Шульц… - Химия в интересах …, 2005 - sibran.ru
Аннотация В обзоре систематизированы данные по природным источникам бетулина
и методам его выделения. Рассмотрены превращения бетулина и его доступных …

Design and synthesis of pentacyclic triterpene conjugates and their use in medicinal research

J Hodon, L Borkova, J Pokorny, A Kazakova… - European journal of …, 2019 - Elsevier
Triterpenoids are natural products from plants and many other organisms that have various
biological activities, such as antitumor, antiviral, antimicrobial, and protective activities. This …

Targeting mitochondrial apoptosis by betulinic acid in human cancers

S Fulda, G Kroemer - Drug discovery today, 2009 - Elsevier
Betulinic acid (BA) is a naturally occurring pentacyclic triterpene that exhibits a variety of
biological activities including potent antitumor properties. This anticancer activity has been …

[PDF][PDF] Betulin and its derivatives. Chemistry and biological activity

GA Tolstikov, OB Flekhter, EE Shultz… - Chemistry for …, 2005 - researchgate.net
The data on natural sources of betulin and methods of its extraction are systematized in the
review. Transformations of betulin and its available derivatives are considered. The data on …

The cytotoxic activity of ursolic acid derivatives

CM Ma, SQ Cai, JR Cui, RQ Wang, PF Tu… - European Journal of …, 2005 - Elsevier
Ursolic acid and 2α-hydroxyursolic acid isolated from apple peels were found to show
growth inhibitory activity against four tumor cell lines, HL-60, BGC, Bel-7402 and Hela …

Pentacyclic triterpenoids with nitrogen-and sulfur-containing heterocycles: synthesis and medicinal significance

M Kvasnica, M Urban, NJ Dickinson, J Sarek - Natural product reports, 2015 - pubs.rsc.org
Covering: 1962 to 2014 Triterpenoids are natural compounds with a variety of biological
activities and are usually produced by plants as secondary metabolites. In recent decades …