Polymersome-based drug-delivery strategies for cancer therapeutics

T Anajafi, S Mallik - Therapeutic delivery, 2015 - Taylor & Francis
Polymersomes are stable vesicles prepared from amphiphilic polymers and are more stable
compared with liposomes. Although these nanovesicles have many attractive properties for …

Functionalized polymersomes for biomedical applications

PV Pawar, SV Gohil, JP Jain, N Kumar - Polymer Chemistry, 2013 - pubs.rsc.org
Polymersomes are latest entry to the drug carrier systems and have proven their utility to
deliver therapeutic agents to specific tissues/organs due to their versatile polymeric …

Overcoming Endosomal Barrier by Amphotericin B-Loaded Dual pH-Responsive PDMA-b-PDPA Micelleplexes for siRNA Delivery

H Yu, Y Zou, Y Wang, X Huang, G Huang, BD Sumer… - ACS …, 2011 - ACS Publications
The endosomal barrier is a major bottleneck for the effective intracellular delivery of siRNA
by nonviral nanocarriers. Here, we report a novel amphotericin B (AmB)-loaded, dual pH …

PLGA nanoparticles and nanosuspensions with amphotericin B: potent in vitro and in vivo alternatives to Fungizone and AmBisome

H Van de Ven, C Paulussen, PB Feijens… - Journal of controlled …, 2012 - Elsevier
This paper describes the development of poly (D, L-lactide-co-glycolide)(PLGA)
nanoparticles (NPs) and nanosuspensions with the polyene antibiotic amphotericin B …

High loading of hydrophilic/hydrophobic doxorubicin into polyphosphazene polymersome for breast cancer therapy

J Xu, Q Zhao, Y Jin, L Qiu - Nanomedicine: Nanotechnology, Biology and …, 2014 - Elsevier
Breast cancer remains one of the most common cancers for females. Drug delivery based on
cancer nanotechnology could improve the performance of some chemotherapeutic …

Polymersomes and their applications in cancer delivery and therapy

L Guan, L Rizzello, G Battaglia - Nanomedicine, 2015 - Taylor & Francis
Polymersomes have been proposed as a platform for drug delivery systems since late 90s.
They are exploited to deliver hydrophilic and/or hydrophobic therapeutic and diagnostic …

Self assembled ionically sodium alginate cross-linked amphotericin B encapsulated glycol chitosan stearate nanoparticles: applicability in better chemotherapy and …

PK Gupta, AK Jaiswal, S Asthana, A Verma… - Pharmaceutical …, 2015 - Springer
Objectives To investigate the applicability, localization, biodistribution and toxicity of self
assembled ionically sodium alginate cross-linked AmB loaded glycol chitosan stearate …

Self assembling polymers as polymersomes for drug delivery

J Prakash Jain, W Yenet Ayen… - Current pharmaceutical …, 2011 - ingentaconnect.com
Polymersomes are one of the most interesting and versatile architectures among various self
assembled systems for drug delivery. The stability and ability to load both hydrophilic and …

Fabrication of lecithin-gum tragacanth muco-adhesive hybrid nano-carrier system for in-vivo performance of Amphotericin B

T Jabri, M Imran, K Rao, I Ali, M Arfan, MR Shah - Carbohydrate polymers, 2018 - Elsevier
Nano-carriers are excellent systems for improving bioavailability of poor aqueous soluble
drugs. This study focuses fabrication of lecithin-gum tragacanth muco-adhesive hybrid NPs …

Practical approaches on the long-acting injections

YC Kim, KA Min, DJ Jang, TY Ahn, JH Min… - Journal of …, 2020 - Springer
Background Over the last several decades, long-acting injections have been studied in
order to overcome such problems as low bioavailability in the oral route, the short durations …