The sleep-deprived human brain

AJ Krause, EB Simon, BA Mander, SM Greer… - Nature Reviews …, 2017 - nature.com
How does a lack of sleep affect our brains? In contrast to the benefits of sleep, frameworks
exploring the impact of sleep loss are relatively lacking. Importantly, the effects of sleep …

Control of sleep and wakefulness

RE Brown, R Basheer, JT McKenna… - Physiological …, 2012 - journals.physiology.org
This review summarizes the brain mechanisms controlling sleep and wakefulness.
Wakefulness promoting systems cause low-voltage, fast activity in the …

Pathophysiology of sleep apnea

JA Dempsey, SC Veasey, BJ Morgan… - Physiological …, 2010 - journals.physiology.org
Sleep-induced apnea and disordered breathing refers to intermittent, cyclical cessations or
reductions of airflow, with or without obstructions of the upper airway (OSA). In the presence …

Obstructive sleep apnea: brain structural changes and neurocognitive function before and after treatment

N Canessa, V Castronovo, SF Cappa… - American journal of …, 2011 - atsjournals.org
Rationale: Obstructive sleep apnea (OSA) is commonly associated with neurocognitive
impairments that have not been consistently related to specific brain structure abnormalities …

The cognitive cost of sleep lost

JG McCoy, RE Strecker - Neurobiology of learning and memory, 2011 - Elsevier
A substantial body of literature supports the intuitive notion that a good night's sleep can
facilitate human cognitive performance the next day. Deficits in attention, learning & memory …

Cognitive impairment in obstructive sleep apnea

K Gagnon, AA Baril, JF Gagnon, M Fortin, A Décary… - Pathologie …, 2014 - Elsevier
Obstructive sleep apnea (OSA) is characterised by repetitive cessation or reduction of
airflow due to upper airway obstructions. These respiratory events lead to chronic sleep …

Sleep disturbance, cognitive decline, and dementia: a review

AMV Wennberg, MN Wu, PB Rosenberg… - Seminars in …, 2017 - thieme-connect.com
Approximately half of older people report sleep disturbances, which are associated with
various health conditions, including neurodegenerative disease and dementia. Indeed, 60 to …

Brain structural changes in obstructive sleep apnea

PM Macey, R Kumar, MA Woo, EM Valladares… - Sleep, 2008 - academic.oup.com
Abstract Study Objectives: Determine whether obstructive sleep apnea (OSA) subjects show
indications of axonal injury. Design: We assessed fiber integrity in OSA and control subjects …

Neurobehavioral morbidity associated with disordered breathing during sleep in children: a comprehensive review

DW Beebe - Sleep, 2006 - academic.oup.com
Abstract Study Objectives: To comprehensively review research on the association between
childhood sleep-disordered breathing (SDB) and neurobehavioral functioning. Design …

Cognitive profile and brain morphological changes in obstructive sleep apnea

F Torelli, N Moscufo, G Garreffa, F Placidi, A Romigi… - Neuroimage, 2011 - Elsevier
Obstructive sleep apnea (OSA) is accompanied by neurocognitive impairment, likely
mediated by injury to various brain regions. We evaluated brain morphological changes in …