[HTML][HTML] Targeted regulation of autophagy using nanoparticles: New insight into cancer therapy

MDA Paskeh, M Entezari, C Clark, A Zabolian… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Normal cells depend on autophagy to maintain cellular homeostasis by recycling damaged
organelles and misfolded proteins and degrading toxic agents. Similar to apoptosis …

Implantable smart hyperthermia nanofibers for cancer therapy: Challenges and opportunities

A Valizadeh, S Asghari, S Abbaspoor… - Wiley …, 2023 - Wiley Online Library
Nanofibers (NFs) with practical drug‐loading capacities, high stability, and controllable
release have caught the attention of investigators due to their potential applications in on …

Encapsulation of thymus vulgaris essential oil in caseinate/gelatin nanocomposite hydrogel: In vitro antibacterial activity and in vivo wound healing potential

SA Alsakhawy, HH Baghdadi, MA El-Shenawy… - International Journal of …, 2022 - Elsevier
Essential oils, derived from aromatic plants, exhibit various pharmacological properties.
Nevertheless, their clinical applications are confronted by various limitations, such as …

D-mannose functionalized MgAl-LDH/Fe-MOF nanocomposite as a new intelligent nanoplatform for MTX and DOX co-drug delivery

M Pooresmaeil, H Namazi - International Journal of Pharmaceutics, 2022 - Elsevier
Commonly the directly administered chemotherapy drugs lack targeting in tumor treatment.
Thus, trying to improve cancer treatment efficiency led us to design a new intelligent system …

Recent progress in proteins-based micelles as drug delivery carriers

A Mustafai, M Zubair, A Hussain, A Ullah - Polymers, 2023 - mdpi.com
Proteins-derived polymeric micelles have gained attention and revolutionized the
biomedical field. Proteins are considered a favorable choice for developing micelles …

Simultaneous encapsulation of dasatinib and celecoxib into caseinate micelles towards improved in vivo anti-breast cancer efficacy with reduced drug toxicity

CA Lamey, N Moussa, MW Helmy, M Haroun… - Journal of Drug Delivery …, 2023 - Elsevier
Breast cancer is the most global dominant cancer among females. Although there are
continuously growing strategies to develop new therapies, the outcomes are usually …

Co-encapsulation of paclitaxel and 5-fluorouracil in folic acid-modified, lipid-encapsulated hollow mesoporous silica nanoparticles for synergistic breast cancer …

H Yin, Q Yan, Y Liu, L Yang, Y Liu, Y Luo, T Chen… - RSC …, 2022 - pubs.rsc.org
A dual-loaded multi-targeted drug delivery nanosystem was constructed to simultaneously
load paclitaxel (PTX) and 5-fluorouracil (5-FU) for targeted delivery and sustained release at …

Smart polymeric nanoparticles with pH-responsive and PEG-detachable properties (II): co-delivery of paclitaxel and VEGF siRNA for synergistic breast cancer therapy …

M Jin, Y Hou, X Quan, L Chen, Z Gao… - International Journal of …, 2021 - Taylor & Francis
Background The dual-loaded nano-delivery system can realize chemotherapeutic drug and
small interfering RNA (siRNA) co-loading as well as enhance the therapeutic effect of drugs …

Preferential binding of polyphenols in blackcurrant extracts with milk proteins and the effects on the bioaccessibility and antioxidant activity of polyphenols

T Mao, FNU Akshit, I Matiwalage, S Sasidharan… - Foods, 2024 - mdpi.com
Milk proteins are well-known delivery agents; however, there is no clear understanding of
the competitive interactions of milk proteins with polyphenols in mixed complex systems …

Significance of chromatographic techniques in pharmaceutical analysis

W Parys, M Dołowy, A Pyka-Pająk - Processes, 2022 - mdpi.com
This work presents an overview of the modern approaches embracing advanced equipment
and validation parameters of both liquid and gas chromatography techniques, including thin …