Tumor-associated exosomes promote lung cancer metastasis through multiple mechanisms
C Jiang, N Zhang, X Hu, H Wang - Molecular Cancer, 2021 - Springer
As an important medium of intercellular communication, exosomes play an important role in
information transmission between tumor cells and their microenvironment. Tumor metastasis …
information transmission between tumor cells and their microenvironment. Tumor metastasis …
Role of metabolic reprogramming in epithelial–mesenchymal transition (EMT)
Activation of epithelial–mesenchymal transition (EMT) is thought to be an essential step for
cancer metastasis. Tumor cells undergo EMT in response to a diverse range of extra-and …
cancer metastasis. Tumor cells undergo EMT in response to a diverse range of extra-and …
Fibroblasts as turned agents in cancer progression
R Wieder - Cancers, 2023 - mdpi.com
Simple Summary Normal epithelial cells in our organs are surrounded by stroma, which is
an ecosystem made up of a variety of cells and proteins that support their intended functions …
an ecosystem made up of a variety of cells and proteins that support their intended functions …
Longitudinal single-cell profiling reveals molecular heterogeneity and tumor-immune evolution in refractory mantle cell lymphoma
The mechanisms driving therapeutic resistance and poor outcomes of mantle cell lymphoma
(MCL) are incompletely understood. We characterize the cellular and molecular …
(MCL) are incompletely understood. We characterize the cellular and molecular …
Genetic alterations of TRAF proteins in human cancers
S Zhu, J Jin, S Gokhale, AM Lu, H Shan… - Frontiers in …, 2018 - frontiersin.org
The tumor necrosis factor receptor (TNF-R)-associated factor (TRAF) family of cytoplasmic
adaptor proteins regulate the signal transduction pathways of a variety of receptors …
adaptor proteins regulate the signal transduction pathways of a variety of receptors …
Role of K63-linked ubiquitination in cancer
L Cao, X Liu, B Zheng, C Xing, J Liu - Cell death discovery, 2022 - nature.com
Ubiquitination is a critical type of post-translational modifications, of which K63-linked
ubiquitination regulates interaction, translocation, and activation of proteins. In recent years …
ubiquitination regulates interaction, translocation, and activation of proteins. In recent years …
MALAT1-regulated gene expression profiling in lung cancer cell lines
J Roh, B Kim, M Im, W Jang, Y Chae, JH Kang… - BMC cancer, 2023 - Springer
Background Non-small cell lung cancer (NSCLC) is the most common type of lung cancer
and has a poor prognosis. Identifying biomarkers based on molecular mechanisms is critical …
and has a poor prognosis. Identifying biomarkers based on molecular mechanisms is critical …
Roles of DNA repair enzyme OGG1 in innate immunity and its significance for lung cancer
S Vlahopoulos, M Adamaki, N Khoury… - Pharmacology & …, 2019 - Elsevier
Cytokines are pivotal mediators of the immune response, and their coordinated expression
protects host tissue from excessive damage and oxidant stress. Nevertheless, the …
protects host tissue from excessive damage and oxidant stress. Nevertheless, the …
Tumor microenvironment: a prospective target of natural alkaloids for cancer treatment
Y Luo, S Yin, J Lu, S Zhou, Y Shao, X Bao… - Cancer Cell …, 2021 - Springer
Malignant tumor has become one of the major diseases that seriously endangers human
health. Numerous studies have demonstrated that tumor microenvironment (TME) is closely …
health. Numerous studies have demonstrated that tumor microenvironment (TME) is closely …
YY1-induced lncRNA ZFPM2-AS1 facilitates cell proliferation and invasion in small cell lung cancer via upregulating of TRAF4
Z Yan, Q Yang, M Xue, S Wang, W Hong, X Gao - Cancer cell international, 2020 - Springer
Background Newly identified lncRNA zinc finger protein, FOG family member 2 antisense
RNA 1 (ZFPM2-AS1) is identified as an oncogenic gene. However, the role of ZFPM2-AS1 in …
RNA 1 (ZFPM2-AS1) is identified as an oncogenic gene. However, the role of ZFPM2-AS1 in …