Trabecular bone is a highly porous, heterogeneous, and anisotropic material which can be
found at the epiphyses of long bones and in the vertebral bodies. Studying the mechanical …

The tissue-level Young's modulus of trabecular bone is important for detailed mechanical
analysis of bone and bone-implant mechanical interactions. However, the heterogeneity and …

In this article, we propose to discretize the problem of linear elastic homogenization by finite
differences on a staggered grid and introduce fast and robust solvers. Our method shares …

Bone has the ability to adapt its shape and size in response to mechanical loads via a
process known as modelling in which bones are shaped or reshaped by the independent …

High‐resolution peripheral quantitative computed tomography (HR‐pQCT) is a newly
developed in vivo clinical imaging modality. It can assess the 3D microstructure of cortical …

Objectives The ability to determine human bone stiffness is of clinical relevance in many
fields, including bone quality assessment and orthopaedic prosthesis design. Stiffness can …

In the context of osteoporosis, evaluation of bone fracture risk and improved design of
epiphyseal bone implants rely on accurate knowledge of the mechanical properties of …

The geometry of a metallic scaffold is important for the success of bone implants, where the
introduction of porosity can reduce stress shielding effects and allow for bone tissue …

Biodegradable polymers and composites are promising candidates for biomedical implants
in tissue engineering. However, state-of-the-art composite scaffolds suffer from a strength …

Recent studies have suggested that extracellular matrix rigidity regulates cancer
invasiveness, including the formation of cellular invadopodial protrusions; however, the …