Human lactoferrin (hLf), an iron-binding multifunctional cationic glycoprotein secreted by
exocrine glands and by neutrophils, is a key element of host defenses. HLf and bovine Lf …

ABSTRACT The coronavirus disease 2019 (COVID-19) pandemic is rapidly advancing
across the globe despite drastic public and personal health measures. Antivirals and …

Iron dyshomeostasis can cause neuronal damage to iron-sensitive brain regions.
Neurodegeneration with brain iron accumulation reflects a group of disorders caused by iron …

As people age, iron deposits in different areas of the brain may impair normal cognitive
function and behavior. Abnormal iron metabolism generates hydroxyl radicals through the …

Despite recent advances in cancer therapy, current treatments, including radiotherapy,
chemotherapy, and immunotherapy, although beneficial, present attendant side effects and …

BACKGROUND: Lactoferrin (Lf) is an 80kDa iron-binding glycoprotein of the transferrin
family. It is abundant in milk and in most biological fluids and is a cell-secreted molecule that …

We report the existence of a previously unknown antimicrobial domain near the N-terminus
of lactoferrin in a region distinct from its iron-binding sites. A single active peptide …

Lactoferrin is a member of the transferrin family of iron-binding proteins. Numerous functions
have been reported and continue to be reported for the protein, some of which are related to …

Lactoferrin, a multifunctional iron binding glycoprotein, plays an important role in immune
regulation and defence mechanisms against bacteria, fungi and viruses. Lactoferrin's iron …

Lactoferrin is a 703-amino acid glycoprotein originally isolated from milk. Plasma lactoferrin
is predominantly neutrophil derived but indications are that it may also be produced by other …