In diverse cell types, microtubule (MT) and actin filament networks cooperate functionally
during a wide variety of processes, including vesicle and organelle transport, cleavage …

▪ Abstract Cytokinesis creates two daughter cells endowed with a complete set of
chromosomes and cytoplasmic organelles. This conceptually simple event is mediated by a …

To elucidate mechanisms that control and execute activity-dependent synaptic plasticity, α-
amino-3-hydroxy-5-methyl-4-isoxazole propionate receptors (AMPA-Rs) with an …

DNA lesions can often block DNA replication, so cells possess specialized low-fidelity, and
often error-prone, DNA polymerases that can bypass such lesions and promote replication …

During epithelial sheet formation, linear actin cables assemble at nascent adherens
junctions. This process requires α-catenin and actin polymerization, although the underlying …

Successful reproduction in mammals requires a competent egg, which is formed during
meiosis through two assymetrical cell divisions. Here, we show that a recently identified …

Coordination of spindle orientation with the axis of cell division is an essential process in all
eukaryotes. In addition to ensuring accurate chromosomal segregation, proper spindle …

Background: Eukaryotic cells localize selected mRNAs to a region of the cell as a means to
sequester proteins. Signals within the 3′ untranslated region (3′ UTR) facilitate mRNA …

Background: Both symmetric and asymmetric cell divisions are required for the generation of
appropriate cell lineages during development. Wild-type Schizosaccharomyces pombe cells …

Correct positioning of the mitotic spindle is critical for cell division and development. Spindle
positioning involves a search-and-capture mechanism whereby dynamic microtubules find …