Silk fibroin has become a prominent material in tissue engineering (TE) over the last 20
years with almost 10,000 published works spanning in all the TE applications, from skeleton …

Background In recent years, cardiovascular disease in particular myocardial infarction (MI)
has become the predominant cause of human disability and mortality in the clinical setting …

Stem cell therapy holds promise for tissue regeneration, yet significant challenges persist.
Emerging as a safer and potentially more effective alternative, extracellular vesicles (EVs) …

Cardiovascular aging presents a formidable challenge, as the aging process can lead to
reduced cardiac function and heightened susceptibility to cardiovascular diseases …

Autophagy maintains cellular homeostasis and plays a crucial role in managing pathological
conditions including ischemic myocardial injury leading to heart failure (HF). Despite …

Cardiovascular diseases are one of the leading global causes of morbidity and mortality,
posing considerable health and economic burden on patients and medical systems …

Cardiovascular diseases (CVDs), including coronary artery disease, stroke, heart failure,
and hypertension, are the global leading causes of death, accounting for more than 30% of …

Bioengineered materials represent an innovative option to support the regenerative
processes of damaged tissues, with the final objective of creating a functional environment …

The adhesion between heart and chest post-operation raises a significant challenge for the
application of cardiac patches due to its severe influences on the recovery of heart function …

Ischemic heart failure (IHF) is a leading cause of morbidity and mortality worldwide, for
which heart transplantation remains the only definitive treatment. IHF manifests from …