The emerging role of the BDNF-TrkB signaling pathway in the modulation of pain perception
The brain derived neurotrophic factor (BDNF) is a crucial neuromodulator in pain
transmission both in peripheral and central nervous system (CNS). Despite evidence of a …
transmission both in peripheral and central nervous system (CNS). Despite evidence of a …
Stress-induced depression and Alzheimer's disease: focus on astrocytes
OV Dolotov, LS Inozemtseva, NF Myasoedov… - International journal of …, 2022 - mdpi.com
Neurodegenerative diseases and depression are multifactorial disorders with a complex
and poorly understood physiopathology. Astrocytes play a key role in the functioning of …
and poorly understood physiopathology. Astrocytes play a key role in the functioning of …
Double stochastic resonance in neuronal dynamics due to astrocytes
A continuously growing body of evidence indicates that astrocytes, which is the most
abundant sub-type of glial cells in the nervous system, not only provide structural and …
abundant sub-type of glial cells in the nervous system, not only provide structural and …
A systematic review of minor phytocannabinoids with promising neuroprotective potential
NL Stone, AJ Murphy, TJ England… - British Journal of …, 2020 - Wiley Online Library
Embase and PubMed were systematically searched for articles addressing the
neuroprotective properties of phytocannabinoids, apart from cannabidiol and Δ9 …
neuroprotective properties of phytocannabinoids, apart from cannabidiol and Δ9 …
Inflammasome activation under high cholesterol load triggers a protective microglial phenotype while promoting neuronal pyroptosis
C de Dios, X Abadin, V Roca-Agujetas… - Translational …, 2023 - Springer
Background Persistent inflammatory response in the brain can lead to tissue damage and
neurodegeneration. In Alzheimer's disease (AD), there is an aberrant activation of …
neurodegeneration. In Alzheimer's disease (AD), there is an aberrant activation of …
[HTML][HTML] Microglial implications in SARS-CoV-2 infection and COVID-19: Lessons from viral RNA neurotropism and possible relevance to Parkinson's disease
Since December 2019, humankind has been experiencing a ravaging severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak, the second coronavirus …
respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak, the second coronavirus …
GDNF, a neuron-derived factor upregulated in glial cells during disease
M Duarte Azevedo, S Sander… - Journal of clinical medicine, 2020 - mdpi.com
In a healthy adult brain, glial cell line-derived neurotrophic factor (GDNF) is exclusively
expressed by neurons, and, in some instances, it has also been shown to derive from a …
expressed by neurons, and, in some instances, it has also been shown to derive from a …
Regulating endogenous neural stem cell activation to promote spinal cord injury repair
EAB Gilbert, N Lakshman, KSK Lau, CM Morshead - Cells, 2022 - mdpi.com
Spinal cord injury (SCI) affects millions of individuals worldwide. Currently, there is no cure,
and treatment options to promote neural recovery are limited. An innovative approach to …
and treatment options to promote neural recovery are limited. An innovative approach to …
[HTML][HTML] The complex role of inflammation and gliotransmitters in Parkinson's disease
Our understanding of the role of innate and adaptive immune cell function in brain health
and how it goes awry during aging and neurodegenerative diseases is still in its infancy …
and how it goes awry during aging and neurodegenerative diseases is still in its infancy …
Current insights into oligodendrocyte metabolism and its power to sculpt the myelin landscape
M Narine, H Colognato - Frontiers in cellular neuroscience, 2022 - frontiersin.org
Once believed to be part of the nervenkitt or “nerve glue” network in the central nervous
system (CNS), oligodendroglial cells now have established roles in key neurological …
system (CNS), oligodendroglial cells now have established roles in key neurological …