Molecular biology, epidemiology, and pathogenesis of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain

MW Ferenczy, LJ Marshall, CDS Nelson… - Clinical microbiology …, 2012 - Am Soc Microbiol
Progressive multifocal leukoencephalopathy (PML) is a debilitating and frequently fatal
central nervous system (CNS) demyelinating disease caused by JC virus (JCV), for which …

Human polyomavirus reactivation: disease pathogenesis and treatment approaches

CF De Gascun, MJ Carr - Journal of Immunology Research, 2013 - Wiley Online Library
JC and BK polyomaviruses were discovered over 40 years ago and have become
increasingly prevalent causes of morbidity and mortality in a variety of distinct …

JC virus evolution and its association with human populations

LA Shackelton, A Rambaut, OG Pybus… - Journal of …, 2006 - Am Soc Microbiol
The ubiquitous human polyomavirus JC (JCV) is a small double-stranded DNA virus that
establishes a persistent infection, and it is often transmitted from parents to children. There …

Deciphering host migrations and origins by means of their microbes

T Wirth, A Meyer, M Achtman - Molecular Ecology, 2005 - Wiley Online Library
Mitochondrial DNA and microsatellite sequences are powerful genetic markers for inferring
the genealogy and the population genetic structure of animals but they have only limited …

Evolution and molecular epidemiology of polyomaviruses

C Torres - Infection, Genetics and Evolution, 2020 - Elsevier
Polyomaviruses (PyVs) are small DNA viruses that infect several species, including
mammals, birds and fishes. Their study gained momentum after the report of previously …

45 years after the discovery of human polyomaviruses BK and JC: time to speed up the understanding of associated diseases and treatment approaches

H Barth, M Solis, Q Lepiller, C Sueur… - Critical reviews in …, 2017 - Taylor & Francis
Nearly 45 years after the discovery of the first two human polyomaviruses BK and JC, their
life-long persistence and mechanisms of pathogenesis remain poorly understood and …

JC polyomavirus circulation in one-year surveillance in wastewater in Santiago, Chile

J Levican, A Levican, M Ampuero, A Gaggero - Infection, Genetics and …, 2019 - Elsevier
Human polyomavirus JC (JCPyV) is a widely distributed viral agent and because it high
resistance against environmental conditions it is frequently recovered from diverse sources …

Entry, infection, replication, and egress of human polyomaviruses: an update

S Bhattacharjee, S Chattaraj - Canadian journal of …, 2017 - cdnsciencepub.com
Polyomaviruses (PyVs), belonging to the family Polyomaviridae, are a group of small,
nonenveloped, double-stranded, circular DNA viruses widely distributed in the vertebrates …

In vitro and in vivo models for the study of human polyomavirus infection

H Barth, M Solis, W Kack-Kack, E Soulier, A Velay… - Viruses, 2016 - mdpi.com
Developments of genome amplification techniques have rapidly expanded the family of
human polyomaviruses (PyV). Following infection early in life, PyV persist in their hosts and …

New sequence polymorphisms in the outer loops of the JC polyomavirus major capsid protein (VP1) possibly associated with progressive multifocal …

HY Zheng, T Takasaka, K Noda… - Journal of general …, 2005 - microbiologyresearch.org
JC polyomavirus (JCPyV) causes progressive multifocal leukoencephalopathy (PML) in
patients with decreased immune competence. To elucidate genetic changes in JCPyV …