Integrating genomic and epidemiologic data to accelerate progress toward schistosomiasis elimination

AJ Lund, KJ Wade, ZL Nikolakis, KN Ivey, BW Perry… - Elife, 2022 - elifesciences.org
The global community has adopted ambitious goals to eliminate schistosomiasis as a public
health problem, and new tools are needed to achieve them. Mass drug administration …

[HTML][HTML] Genome-based tools for onchocerciasis elimination: Utility of the mitochondrial genome for delineating Onchocerca volvulus transmission zones

KE Crawford, SM Hedtke, SR Doyle, AC Kuesel… - International Journal for …, 2024 - Elsevier
National programs in Africa have expanded their objectives from control of onchocerciasis
(river blindness) as a public health problem to elimination of parasite transmission …

R H: a genetic metric for measuring intrahost Plasmodium falciparum relatedness and distinguishing cotransmission from superinfection

W Wong, S Volkman, R Daniels, S Schaffner, M Sy… - PNAS …, 2022 - academic.oup.com
Multiple-strain (polygenomic) infections are a ubiquitous feature of Plasmodium falciparum
parasite population genetics. Under simple assumptions of superinfection, polygenomic …

Slaying the Serpent: A Research Agenda to Expand Intervention Development and Accelerate Guinea Worm Eradication Efforts

MG Delea, A Sack, OA Eneanya… - … American Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Dracunculiasis, also known as Guinea worm disease, is targeted to become the second
human disease and first parasitic infection to be eradicated. The global Guinea Worm …

Predicting the Environmental Suitability and Identifying Climate and Sociodemographic Correlates of Guinea Worm (Dracunculus medinensis) in Chad

OA Eneanya, MG Delea, J Cano… - … American Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
A comprehensive understanding of the spatial distribution and correlates of infection are key
for the planning of disease control programs and assessing the feasibility of elimination …

Modeling the levels, trends, and connectivity of malaria transmission using genomic data from a health facility in Thiès, Senegal

A Lee, YD Ndiaye, A Badiane, A Deme, RF Daniels… - medRxiv, 2021 - medrxiv.org
Molecular data and analysis outputs are being integrated into malaria surveillance efforts to
provide valuable programmatic insights for national malaria control programs (NMCPs). A …

Epidemiological and molecular investigations of a point-source outbreak of Dracunculus medinensis infecting humans and dogs in Chad: a cross-sectional study

SAJ Guagliardo, E Thiele, K Unterwegner… - The Lancet …, 2022 - thelancet.com
Background Dracunculiasis (also known as Guinea worm disease), caused by the
Dracunculus medinensis nematode, is progressing towards eradication, with a reduction in …

LEVERAGING POPULATION GENOMICS ACROSS TWO TAXONOMICALLY DIVERSE NON-MODEL SYSTEMS TO UNDERSTAND PATTERNS OF DISEASE …

ZL Nikolakis - 2023 - mavmatrix.uta.edu
The field of population genomics has been mainly applied to questions centered around
understanding molecular variation, impacts of evolutionary processes, and the history of …