Heme-oxygenase and lipid mediators in obesity and associated cardiometabolic diseases: Therapeutic implications

JA McClung, L Levy, V Garcia, DE Stec… - Pharmacology & …, 2022 - Elsevier
Obesity-mediated metabolic syndrome remains the leading cause of death worldwide.
Among many potential targets for pharmacological intervention, a promising strategy …

Epoxyeicosatrienoic acid as therapy for diabetic and ischemic cardiomyopathy

M Romashko, J Schragenheim, NG Abraham… - Trends in …, 2016 - cell.com
Cardiovascular disease remains the leading cause of death worldwide. Among many
potential targets for pharmacological intervention, a promising strategy involves …

[PDF][PDF] Effect of adiponectin on the steroidogenic acute regulatory protein, P450 side chain cleavage enzyme and 3β-hydroxysteroid dehydrogenase gene expression …

N Smolinska, K Dobrzyn, M Kiezun… - J. Physiol …, 2016 - researchgate.net
Adiponectin and its receptors are expressed in the human and porcine uterus and this
endocrine system has important role in the regulation of reproductive processes. The …

miR-30a attenuates cardiac fibrosis in rats with myocardial infarction by inhibiting CTGF

L Chen, Q Ji, H Zhu, Y Ren… - Experimental and …, 2018 - spandidos-publications.com
The mechanism of miR-30a in myocardial fibrosis in rats with myocardial infarction (MI) was
investigated. rAAV9-miR-30a was constructed and transfected to heart via injecting into the …

Diet: a specific part of the Western lifestyle pack in the asthma epidemic

C Frontela-Saseta, CA González-Bermúdez… - Journal of clinical …, 2020 - mdpi.com
The Western lifestyle is a complex concept that includes the diet as the main axis of different
factors which contribute to a detrimental effect on health, lower life expectancy and low …

Ischemia‐induced cardiac dysfunction is exacerbated in adiponectin‐knockout mice due to impaired autophagy flux

HK Sung, J Tang, JWS Jahng, E Song… - Clinical and …, 2024 - Wiley Online Library
Strategies to enhance autophagy flux have been suggested to improve outcomes in cardiac
ischemic models. We explored the role of adiponectin in mediating cardiac autophagy under …

[PDF][PDF] Association of adiponectin and leptin-to-adiponectin ratio with the function of platelets in morbidly obese patients

I Iwan-Zietek, B Ruszkowska-Ciastek… - J Physiol …, 2016 - jpp.krakow.pl
Adipokines regulate glucose homeostasis, insulin sensitivity, lipids metabolism,
reproduction, as well as endothelial and platelets function. The study compares the plasma …

Microvascular Obstruction and Intramyocardial Hemorrhage in Reperfused Myocardial Infarctions: Pathophysiology and Clinical Insights From Imaging

KP Vora, A Kumar, MS Krishnam, FS Prato… - JACC: Cardiovascular …, 2024 - Elsevier
Microvascular injury immediately following reperfusion therapy in acute myocardial
infarction (MI) has emerged as a driving force behind major adverse cardiovascular events …

Autoantibodies Against β1‐Adrenoceptor Exaggerated Ventricular Remodeling by Inhibiting CTRP9 Expression

Y Du, S Zhang, H Yu, Y Wu, N Cao… - Journal of the …, 2019 - Am Heart Assoc
Background Autoantibodies against the second extracellular loop of the β1‐adrenoceptor
(β1‐AA) act similarly to agonist of β1‐adrenergic receptor, which plays an important role in …

Susceptibility of multiple polymorphisms in ADIPOQ, ADIPOR1 and ADIPOR2 genes to myocardial infarction in Han Chinese

Z Zhang, Y Li, X Yang, L Wang, L Xu, Q Zhang - Gene, 2018 - Elsevier
We aimed to investigate the association of 12 extensively studied polymorphisms in
adiponectin (ADIPOQ), adiponectin receptor-1 (ADIPOR1) and adiponectin receptor-2 …