Reinvigorating exhausted CD8+ cytotoxic T lymphocytes in the tumor microenvironment and current strategies in cancer immunotherapy

MA Hossain, G Liu, B Dai, Y Si, Q Yang… - Medicinal Research …, 2021 - Wiley Online Library
Immunotherapy has revolutionized the treatment of cancer in recent years and achieved
overall success and long‐term clinical benefit in patients with a wide variety of cancer types …

TOX: a rediscovered master molecular actor to enhance immuno-oncology interventions

AA Vertès - Cellular & Molecular Immunology, 2020 - nature.com
Checkpoint blockade therapy and adoptive therapy with engineered human immune effector
cells are paradigm-changing innovations that have already revolutionized the treatment of …