Biocatalysis harnesses enzymes to make valuable products. This green technology is used
in countless applications from bench scale to industrial production and allows practitioners …

Recent progress in engineering highly promising biocatalysts has increasingly involved
machine learning methods. These methods leverage existing experimental and simulation …

Enzyme function annotation is a fundamental challenge, and numerous computational tools
have been developed. However, most of these tools cannot accurately predict functional …

Enzymes can be engineered at the level of their amino acid sequences to optimize key
properties such as expression, stability, substrate range, and catalytic efficiency─ or even to …

Chiral amines are pivotal building blocks for the pharmaceutical industry. Asymmetric
reductive amination is one of the most efficient and atom economic methodologies for the …

Drug discovery and development is a time-consuming process that involves identifying,
designing, and testing new drugs to address critical medical needs. In recent years, machine …

Natural products (NPs) produced by microorganisms and plants are a major source of drugs,
herbicides, and fungicides. Thanks to recent advances in DNA sequencing, bioinformatics …

This review analyzes a development in biochemistry, enzymology and biotechnology that
originally came as a surprise. Following the establishment of directed evolution of …

Production of commodity chemicals, such as benzene, toluene, ethylbenzene, and xylenes
(BTEX), from renewable resources is key for a sustainable society. Biocatalysis enables one …

Bioremediation, an advanced and environmentally sustainable technology, utilizes
biological microorganisms to mitigate pollution. This review combines insights from two …