Substance P is a peptide mainly secreted by neurons and is involved in many biological
processes, including nociception and inflammation. Animal models have provided insights …

Nociceptors and immune cells both protect the host from potential threats to homeostasis.
There is growing evidence for bidirectional signalling between these two systems, and the …

Quercetin is a common antioxidant flavonoid found in vegetables, which is usually present in
glycosylated forms, such as quercitrin (3‐rhamnosylquercetin). Previous in vitro experiments …

Ulcerative colitis (UC) manifests as an etiologically complicated and relapsing
gastrointestinal disease. The enteric nervous system (ENS) plays a pivotal role in rectifying …

BACKGROUND & AIMS: The neuropeptides calcitonin gene-related peptide (CGRP) and
substance P, and calcium channels, which control their release from extrinsic sensory …

Quercitrin, 3‐rhamnosylquercetin, is a bioflavonoid with antioxidant properties, which exerts
anti‐inflammatory activity in experimental colitis. In the present study, different in vivo …

Background and aims: The role of sensory neurones in colitis was studied by chemical
denervation of primary sensory neurones as well as antagonism of the vanilloid receptor-1 …

BACKGROUND AND AIMS: There is increased interest in the study of manipulation of the
flora with pro-and prebiotics regarding inflammatory bowel disease. The aim of this work …

Previous studies proposed a protective role of the dietary intake of (n-3) PUFA in human
inflammatory bowel disease (IBD), but almost no studies have been performed using olive …

Ulcerative colitis (UC) is one of the major inflammatory disorders of the gastrointestinal tract.
α-Terpineol (αTL) is naturally present in several plants, and it belongs to the monoterpenes …