Document Reviewers: Luis Alcocer (Mexico), Christina Antza (Greece), Mustafa Arici
(Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luıs Bronze (Portugal), John …

Resistant hypertension (RH) is a severe form of hypertension associated with increased
cardiovascular risk. Although true RH affects less than 10% of the patients receiving …

Background Despite optimal medical therapy, a significant proportion of patients' blood
pressure remains uncontrolled. Catheter‐based renal denervation (RDN) has been …

Document Reviewers: Luis Alcocer (Mexico), Christina Antza (Greece), Mustafa Arici
(Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luıs Bronze (Portugal), John …

Background Renal denervation (RDN) reduces blood pressure (BP) in patients with
uncontrolled hypertension in the absence of antihypertensive medications. Objectives This …

BACKGROUND: The randomized, sham-controlled RADIANCE-HTN (A Study of the Recor
Medical Paradise System in Clinical Hypertension) SOLO, RADIANCE-HTN TRIO, and …

Renal denervation as an option for difficult to treat hypertension has been a concept for
several decades, with recent US FDA approval of new, minimally invasive devices …

Background Hypertension is a major public health issue due to its association with
cardiovascular disease risk. Despite the availability of effective antihypertensive drugs, rates …

Studies of renal denervation continue to find a robust antihypertensive effect, especially in
studies wherein medications are withdrawn. Further investigation into mechanisms and …

Resistant hypertension is associated with an exceedingly high cardiovascular risk and there
remains an unmet therapeutic need driven by pathophysiologic pathways unaddressed by …