Angiogenesis plays a key role in the pathological process of inflammation and invasion of
the synovium, and primarily drives the progression of rheumatoid arthritis (RA). Recent …

Cutaneous wounds, both acute and chronic, begin with loss of the integrity, and thus barrier
function, of the skin. Surgery and trauma produce acute wounds. There are 22 million …

Langerhans cells (LCs) are distinct among phagocytes, functioning both as embryo-derived,
tissue-resident macrophages in skin innervation and repair and as migrating professional …

Organ injury stimulates the formation of new capillaries to restore blood supply raising
questions about the potential contribution of neoangiogenic vessel architecture to the …

Checkpoint inhibitors have revolutionized cancer treatment, but resistance remains a
significant clinical challenge. Myeloid cells within the tumor microenvironment can modulate …

Langerhans cells (LCs) are resident dendritic cells in the epidermis and their roles in
presenting antigens derived from microorganisms present in the skin has been well …

Our skin is home to a diverse community of commensal microorganisms integral to
cutaneous function. However, microbial dysbiosis and barrier perturbation increase the risk …

Immune metabolism is a result of many specific metabolic reactions, such as glycolysis, the
tricarboxylic acid (TCA) pathway, the pentose phosphate pathway (PPP), mitochondrial …

Apoptosis and clearance of apoptotic cells via efferocytosis are evolutionarily conserved
processes that drive tissue repair. However, the mechanisms by which recognition and …

Cutaneous wound healing is a complex biological process involving a series of well-
coordinated events aimed at restoring skin integrity and function. Various experimental …