Designing nanozymes for in vivo applications

R Zhang, B Jiang, K Fan, L Gao, X Yan - Nature Reviews …, 2024 - nature.com
Biocatalytic drugs, including natural and artificial enzymes that can accelerate biochemical
reactions, are promising tools to address redox imbalances, metabolic disorders and …

Osteoporotic osseointegration: therapeutic hallmarks and engineering strategies

J Chen, Z Hao, H Li, J Wang, T Chen, Y Wang… - …, 2024 - pmc.ncbi.nlm.nih.gov
Osteoporosis is a systemic skeletal disease caused by an imbalance between bone
resorption and formation. Current treatments primarily involve systemic medication and …

[HTML][HTML] BaP/BPDE suppressed endothelial cell angiogenesis to induce miscarriage by promoting MARCHF1/GPX4-mediated ferroptosis

Y Zhang, Y Yang, W Chen, C Mi, X Xu, Y Shen… - Environment …, 2023 - Elsevier
Environmental benzo (a) pyrene (BaP) and its ultimate metabolite BPDE (benzo (a) pyrene-
7, 8-dihydrodiol-9, 10-epoxide) are universal and inevitable persistent organic pollutants …

A Glutathione Peroxidase‐Mimicking Nanozyme Precisely Alleviates Reactive Oxygen Species and Promotes Periodontal Bone Regeneration

B Zhu, J Wu, T Li, S Liu, J Guo, Y Yu… - Advanced …, 2024 - Wiley Online Library
The use of oxidoreductase nanozymes to regulate reactive oxygen species (ROS) has
gradually emerged in periodontology treatments. However, current nanozymes for treating …

Multifunctional scaffolds for bone repair following age-related biological decline: Promising prospects for smart biomaterial-driven technologies

JD Schwartzman, M McCall, Y Ghattas… - Biomaterials, 2024 - Elsevier
The repair of large bone defects due to trauma, disease, and infection can be exceptionally
challenging in the elderly. Despite best clinical practice, bone regeneration within …

Surface chemistry of biologically active reducible oxide nanozymes

CJ Neal, E Kolanthai, F Wei, M Coathup… - Advanced …, 2024 - Wiley Online Library
Reducible metal oxide nanozymes (rNZs) are a subject of intense recent interest due to their
catalytic nature, ease of synthesis, and complex surface character. Such materials contain …

Exploring the emerging trends in the synthesis and theranostic paradigms of cerium oxide nanoparticles (CeONPs): A comprehensive review

S Nag, O Mitra, P Sankarganesh… - Materials Today …, 2024 - Elsevier
Cerium oxide nanoparticles (CeONPs) have come to prominence as a highly intriguing and
beneficial nanomaterial in an array of biomedical and theranostic applications, including …

Nanotechnology enabled radioprotectants to reduce space radiation‐induced reactive oxidative species

B Babu, S Pawar, A Mittal, E Kolanthai… - Wiley …, 2023 - Wiley Online Library
Interest in space exploration has seen substantial growth following recent launch and
operation of modern space technologies. In particular, the possibility of travel beyond low …

Emerging nanozymes in neurological disorder therapeutics: bridging oxidoreductase mimicry and antioxidant chemistry

G Jiang, Q Xu, J Xie, Y You, L Cai… - Advanced Functional …, 2024 - Wiley Online Library
The prevalence of neurological dieases, including neurodegenerative, neurotraumatic
disorders, and neuroinflammatory conditions, has been rising due to global population and …

Nanozymes With Osteochondral Regenerative Effects: An Overview of Mechanisms and Recent Applications

X Sun, X Xu, X Yue, T Wang, Z Wang… - Advanced …, 2024 - Wiley Online Library
With the discovery of the intrinsic enzyme‐like activity of metal oxides, nanozymes garner
significant attention due to their superior characteristics, such as low cost, high stability, multi …