Epithelial-to-mesenchymal transition (EMT) is a step-wise process observed in normal and tumor cells leading to a switch from epithelial to mesenchymal phenotype. In tumors, EMT …
Y Ding, F Cao, H Sun, Y Wang, S Liu, Y Wu, Q Cui… - Cancer letters, 2019 - Elsevier
The roles of miRNAs in the development of cancer have made them promising tools for novel therapeutic approaches. However, the successful delivery of miRNAs to cancer cells …
R Gradiz, HC Silva, L Carvalho, MF Botelho… - Scientific reports, 2016 - nature.com
Studies using cell lines should always characterize these cells to ensure that the results are not distorted by unexpected morphological or genetic changes possibly due to culture time …
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive malignancies to date, largely because it is associated with high metastatic risk. Pancreatic …
M Shan, D Yang, H Dou, L Zhang - Progress in molecular biology and …, 2019 - Elsevier
Fucosylation is the process of transferring fucose from GDP-fucose to their substrates, which includes certain proteins, N-and O-linked glycans in glycoprotein or glycolipids, by …
Resveratrol and quercetin are phytochemicals that are found in a variety of plants. The aim of this study was to investigate the effect of resveratrol and quercetin on epithelial …
M Giulietti, G Occhipinti, G Principato, F Piva - Cellular Oncology, 2016 - Springer
Purpose Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy. Up till now, the patient's prognosis remains poor which, among others, is due to the paucity of …
M Miquel, S Zhang, C Pilarsky - Frontiers in cell and developmental …, 2021 - frontiersin.org
Pancreatic ductal adenocarcinoma (PDAC) is a hostile solid malignancy coupled with an extremely high mortality rate. Metastatic disease is already found in most patients at the time …
J Hu, LE Li, H Chen, G Zhang, H Liu, R Kong… - Cell Death & …, 2018 - nature.com
Metastasis remains one of the most intractable challenges in pancreatic ductal adenocarcinoma (PDAC) biology, and epithelial-to-mesenchymal transition (EMT) is …