The emerging and powerful field of spatial pharmacology can map the spatial distribution of
drugs and their metabolites, as well as their effects on endogenous biomolecules including …

Nowadays, matrix-assisted laser desorption/ionization time of flight mass spectrometry
(MALDI-TOF MS) is routinely implemented as the reference method for the swift and …

Mass spectrometry imaging (MSI) techniques generate data that reveal spatial distributions
of molecules on a surface with high sensitivity and selectivity. However, processing large …

Modern researches on medicines and foods have proposed greatly increasing demand on
the spatial distribution analysis of the medicinal and edible plants (MEPs). Mass …

The recent upswing in the integration of spatial multi-omics for conducting multidimensional
information measurements is opening a new chapter in biological research. Mapping the …

Ion mobility spectrometry‐mass spectrometry (IMS‐MS or IM‐MS) is a powerful analytical
technique that combines the gas‐phase separation capabilities of IM with the identification …

Imaging mass spectrometry is a powerful technology enabling spatial metabolomics, yet
metabolites can be assigned only to a fraction of the data generated. METASPACE-ML is a …

Mass spectrometric innovations in analytical instrumentation tend to be accompanied by the
development of a data-processing methodology, expecting to gain molecular-level insights …

Herbivorous insects encounter diverse plant specialized metabolites (PSMs) in their diet,
that have deterrent, anti-nutritional, or toxic properties. Understanding how they cope with …

Highlights•Current strategies to map lipids, metabolites, and proteins in tumor
tissues.•Recent biological insights obtained from MSI of tumor samples.•Challenges in …