[HTML][HTML] Chlorogenic acid: Potential source of natural drugs for the therapeutics of fibrosis and cancer

EO Nwafor, P Lu, Y Zhang, R Liu, H Peng, B Xing… - Translational …, 2022 - Elsevier
Fibrosis and cancer is described by some epidemiological studies as chronic stages of
different disease conditions typically characterized by uncontrolled accumulation of extra …

A review of the protective effects of chlorogenic acid against different chemicals

R Rashidi, R Rezaee, A Shakeri… - Journal of Food …, 2022 - Wiley Online Library
Chlorogenic acid (CGA) is a naturally occurring non‐flavonoid polyphenol found in green
coffee beans, teas, certain fruits, and vegetables, that exerts antiviral, antitumor …

Zingerone reduces sodium arsenite-induced nephrotoxicity by regulating oxidative stress, inflammation, apoptosis and histopathological changes

N Akaras, C Gur, S Kucukler, FM Kandemir - Chemico-biological …, 2023 - Elsevier
Arsenic is widely available in the environment and arsenic toxicity is a public health problem
of serious concern worldwide. Zingerone is a promising phytochemical with various …

Exploring the multifaceted potential of chlorogenic acid: Journey from nutraceutical to nanomedicine

SK Singh, K Thakur, V Sharma, M Saini… - South African Journal of …, 2023 - Elsevier
Chlorogenic acid (CGA) is a naturally occurring polyphenolic acid from the family of
hydroxycinnamic acid, often found in green coffee extract and tea. CGA is chemically called …

Chlorogenic acid abates male reproductive dysfunction in arsenic-exposed mice via attenuation of testicular oxido-inflammatory stress and apoptotic responses

MF El-Khadragy, WA Al-Megrin, S Alomar… - Chemico-biological …, 2021 - Elsevier
Arsenic, a major environmental pollutant of global concern, is well-known for its reproductive
toxicity. In this study, the protective potential of chlorogenic acid (CGA), a caffeoylquinic acid …

Hawthorn fruit acid consumption attenuates hyperlipidemia-associated oxidative damage in rats

Y Feng, S Gao, T Zhu, G Sun, P Zhang, Y Huang… - Frontiers in …, 2022 - frontiersin.org
Context Hyperlipidemia is a highly prevalent risk factor for atherosclerosis and stroke. The
currently available medications used to treat Hyperlipidemia cannot improve its oxidative …

[HTML][HTML] Chlorogenic acid confers robust neuroprotection against arsenite toxicity in mice by reversing oxidative stress, inflammation, and apoptosis

DM Metwally, RA Alajmi, MF El-Khadragy… - Journal of functional …, 2020 - Elsevier
Arsenic is a potent neurotoxic xenobiotic found in drinking water, and food. Chlorogenic acid
(CGA), an abundant polyphenol in coffee, potentially has a wide range of therapeutic …

Protective efficacy of thymoquinone or ebselen separately against arsenic-induced hepatotoxicity in rat

D Al Aboud, RS Baty, KF Alsharif, KE Hassan… - … Science and Pollution …, 2021 - Springer
Arsenic (As) exposure is associated with adverse health outcomes to the living organisms. In
the present study, the hepato-protective ability of thymoquinone (TQ), the active principle of …

TLR4/inflammasomes cross-talk and pyroptosis contribute to N-Acetyl cysteine and chlorogenic acid protection against cisplatin-induced nephrotoxicity

AM Badr, LA Al-Kharashi, H Attia, S Alshehri… - Pharmaceuticals, 2023 - mdpi.com
Background: Cisplatin (Cp) is an antineoplastic agent with a dose-limiting nephrotoxicity. Cp-
induced nephrotoxicity is characterized by the interplay of oxidative stress, inflammation …

Neuroprotective role of chlorogenic acid against hippocampal neuroinflammation, oxidative stress, and apoptosis following acute seizures induced by …

HA Althagafi - Metabolic Brain Disease, 2024 - Springer
This study investigated the neuroprotective effect of chlorogenic acid (CGA) on
pentylenetetrazole (PTZ)-induced acute epileptic seizures in mice. Epileptic animals …