Acute lung injury (ALI) is a syndrome associated with a high mortality rate. Nrf2 is a key
regulator of intracellular oxidation homeostasis that plays a pivotal role in controlling lipid …

Significance: The transcription factor NRF2 (NF-E2-related factor 2) plays an important role
as a master regulator of the cellular defense system by activating transcriptional programs of …

The prevalence of chronic diseases has increased significantly with the rising trend of
sedentary lifestyles, reduced physical activity, and dietary modifications in recent decades …

Acute lung injury (ALI) carries a mortality rate of~ 50% and is a hot topic in the world of
critical illness research. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a critical …

Ischemia/reperfusion (IR)-induced acute lung injury (ALI) has a high mortality rate. Reactive
oxygen species (ROS) play a crucial role in causing cellular damage and death in IR …

Background Inflammation and oxidative stress is closely associated with the development of
ischemic brain stroke. Opa-interacting protein 5 antisense RNA 1 (OIP5-AS1), a novel …

Background and Aim: The global pandemic of COVID-19 has posed an enormous threat to
the economy and people's lives across various countries. Patients with COVID-19 most …

Background Intestinal ischemia/reperfusion (I/R) is a common clinical problem that occurs
during various clinical pathological processes. Dexmedetomidine (DEX), a widely used …

Aims. Ischemic postconditioning (IPO) has a strong protective effect against intestinal
ischemia‐reperfusion (IIR) injury that is partly related to autophagy. However, the precise …

Mercury is a key global pollutant, yet the mechanism by which mercury-exposure causes
intestinal injury is not clear, we aimed to investigate the mechanism of intestinal injury and …