Pregnancy considerations in the multidisciplinary care of patients with pulmonary arterial hypertension

J Coursen, CE Simpson, M Mukherjee… - Journal of …, 2022 - mdpi.com
Pulmonary arterial hypertension (PAH) is a vasoconstrictive disease of the distal pulmonary
vasculature resulting in adverse right heart remodeling. Pregnancy in PAH patients is …

[HTML][HTML] Dobbs and disability: Implications of abortion restrictions for people with chronic health conditions

A Hassan, L Yates, AK Hing, AE Hirz… - Health services …, 2023 - ncbi.nlm.nih.gov
The United States has a long history of undermining the reproductive autonomy of people
with chronic conditions. This includes people with disabilities that are seen or unseen, and …

Assessment of the risk evaluation and mitigation strategy (REMS) for phentermine–topiramate to prevent exposure during pregnancy

A Sarayani, WT Donahoo, C Hampp… - Annals of Internal …, 2023 - acpjournals.org
Background: The US Food and Drug Administration approved phentermine–topiramate for
obesity in 2012 and required a Risk Evaluation and Mitigation Strategy (REMS) to prevent …

Reproductive health care for female adolescents prescribed mycophenolate at a children's hospital: a 10-Year retrospective cohort study

N Al-Husayni, S Maslyanskaya, TB Rubinstein… - The Journal of …, 2023 - Elsevier
Objectives To describe female adolescents' reproductive health needs and subspecialists'
teratogenic counseling at initiation of mycophenolate as well as use of reproductive health …

Unintended consequences of SCOTUS abortion decision for patients with rheumatic diseases

MEB Clowse, KG Saag - Annals of Internal Medicine, 2022 - acpjournals.org
This article discusses the Supreme Court's ruling in Dobbs v. Jackson and the concerns it
raises for patients with rheumatic disease and their clinicians, including access to medically …

Topiramate utilization after phentermine/topiramate approval for obesity management: risk minimization in the era of drug repurposing

A Sarayani, C Hampp, JD Brown, WT Donahoo… - Drug Safety, 2022 - Springer
Abstract Introduction The US FDA required a Risk Evaluation and Mitigation Strategy
(REMS) for phentermine/topiramate, an anti-obesity medication, to prevent congenital …

Prenatal Exposure to Valproic Acid Across Various Indications for Use

NE Smolinski, A Sarayani, TN Thai, S Jugl… - JAMA Network …, 2024 - jamanetwork.com
Importance Teratogenic outcomes associated with valproic acid use represent a substantial
concern for persons of childbearing age. Regulatory agencies worldwide have enhanced …

Common teratogenic medication exposures—a population-based study of pregnancies in the United States

Y Wang, NE Smolinski, TN Thai, A Sarayani… - American Journal of …, 2024 - Elsevier
BACKGROUND Risk mitigation for most teratogenic medications relies on risk
communication via drug label, and prenatal exposures remain common. Information on the …

Early statin exposure influences cardiac and skeletal development with implications for ion channel transcriptomes in zebrafish

Y Zhao, HZ Yang, H Li, S Liang, M Wang, CD Li… - … and Physiology Part C …, 2024 - Elsevier
Statins, widely prescribed for cholesterol management by inhibiting HMG-CoA reductase in
the cholesterol biosynthesis pathway, may also influence vertebrate development. In this …

Neurodevelopmental disorders after prenatal exposure to topiramate: A lost decade idly watching from the sidelines

A Braillon - Seizure-European Journal of Epilepsy, 2023 - seizure-journal.com
Knight and colleagues must be commended for their cross-sectional study from the UK
Epilepsy and Pregnancy Register evidencing that children exposed to topiramate in utero …