Ari Helenius launched the field of enveloped virus fusion in endosomes with a seminal
paper in the Journal of Cell Biology in 1980. In the intervening years, a great deal has been …

Viruses depend on their hosts to complete their replication cycles; they exploit cellular
receptors for entry and hijack cellular functions to replicate their genome, assemble progeny …

Broadly protective vaccines against known and preemergent human coronaviruses (HCoVs)
are urgently needed. To gain a deeper understanding of cross-neutralizing antibody …

The Coronaviridae are a family of viruses that cause disease in humans ranging from mild
respiratory infection to potentially lethal acute respiratory distress syndrome. Finding host …

Summary The coronavirus disease 2019 (COVID-19) pandemic has claimed the lives of
over one million people worldwide. The causative agent, severe acute respiratory syndrome …

Here we describe the complete genome of a new ebolavirus, Bombali virus (BOMV)
detected in free-tailed bats in Sierra Leone (little free-tailed (Chaerephon pumilus) and …

There is an urgent need for vaccines and therapeutics to prevent and treat COVID-19. Rapid
SARS-CoV-2 countermeasure development is contingent on the availability of robust …

Viruses are obligate intracellular microbes that exploit the host metabolic machineries to
meet their biosynthetic demands, making these host pathways potential therapeutic targets …

Abstract Ever-evolving SARS-CoV-2 variants of concern (VOCs) have diminished the
effectiveness of therapeutic antibodies and vaccines. Developing a coronavirus vaccine that …

There are several reasons to consider the role of endothelial cells in COVID-19 and other
emerging viral infections. First, severe cases of COVID-19 show a common breakdown of …