Progress in molecular biology has made available new bioanalytical tools that take
advantage of the great detectability and the simple analytical format of bioluminescence …

The rise of infectious diseases as a public health concern has necessitated the development
of rapid and precise diagnostic methods. Imaging techniques like nuclear and optical …

There is an increasing need for versatile yet sensitive labels, posed by the demands for low
detection in bioanalysis. Bioluminescent proteins have many desirable characteristics …

A fundamental molecular beacon (MB) consists of a special short nucleic acid strand with a
fluorophore-quencher pair attached to its ends. It provides a unique framework that is …

In this work, the photophysical properties of two oxazine dyes (ATTO 610 and ATTO 680)
covalently attached via a C6-amino linker to the 5′-end of short single-stranded as well as …

MiRNAs are valuable biomarkers for diagnosis and prognosis of cancers, so it is imperative
to develop rapid, sensitive, high throughput miRNA detection methods. In this review article …

RNA has been recognized as an important biomarker of many infectious pathogens; thus,
sensitive, simple and rapid detection of RNA is urgently required for the control of epidemics …

Protein misfolding, aggregation, and accumulation are critically important attributes resulting
in cellular malfunction, synapse loss, and brain damage, which are the hallmark of …

The miRNAs are valuable biomarkers for the diagnosis and prognosis of gastric cancer. This
chapter summarizes current advances of microRNA biomarkers of gastric cancer; especially …

Wir haben DNA-basierte Hybridisierungssonden zur erzwungenen Interkalation
(sogenannte FIT-Sonden) entwickelt. Diese beruhen auf dem Ersatz einer natürlichen …