COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection

WY Chi, YD Li, HC Huang, TEH Chan, SY Chow… - Journal of biomedical …, 2022 - Springer
Abstract Coronavirus Disease 2019 (COVID-19) has been the most severe public health
challenge in this century. Two years after its emergence, the rapid development and …

SARS-CoV-2 breakthrough infections in vaccinated individuals: measurement, causes and impact

M Lipsitch, F Krammer, G Regev-Yochay… - Nature Reviews …, 2022 - nature.com
Breakthrough infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) in fully vaccinated individuals are receiving intense scrutiny because of their importance …

Unadjuvanted intranasal spike vaccine elicits protective mucosal immunity against sarbecoviruses

T Mao, B Israelow, MA Peña-Hernández, A Suberi… - Science, 2022 - science.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
highlighted the need for vaccines that not only prevent disease but also prevent …

COVID-19 vaccine waning and effectiveness and side-effects of boosters: a prospective community study from the ZOE COVID Study

C Menni, A May, L Polidori, P Louca, J Wolf… - The Lancet Infectious …, 2022 - thelancet.com
Background With the surge of new SARS-CoV-2 variants, countries have begun offering
COVID-19 vaccine booster doses to high-risk groups and, more recently, to the adult …

Final analysis of efficacy and safety of single-dose Ad26. COV2. S

J Sadoff, G Gray, A Vandebosch… - … England Journal of …, 2022 - Mass Medical Soc
Abstract Background The Ad26. COV2. S vaccine was highly effective against severe–
critical coronavirus disease 2019 (Covid-19), hospitalization, and death in the primary phase …

OMICRON (B. 1.1. 529): a new SARS‐CoV‐2 variant of concern mounting worldwide fear

V Thakur, RK Ratho - Journal of medical virology, 2022 - Wiley Online Library
Recent emergence of the SARS‐CoV‐2 variant as OMICRON has become a global concern.
This short note highlights the identification and global spread of OMICRON which has …

Nanotechnology-based strategies against SARS-CoV-2 variants

X Huang, E Kon, X Han, X Zhang, N Kong… - Nature …, 2022 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has already infected more
than 500 million people globally (as of May 2022), creating the coronavirus disease 2019 …

Limited neutralisation of the SARS-CoV-2 Omicron subvariants BA. 1 and BA. 2 by convalescent and vaccine serum and monoclonal antibodies

A Wilhelm, M Widera, K Grikscheit, T Toptan… - …, 2022 - thelancet.com
Summary Background In recent months, Omicron variants of SARS-CoV-2 have become
dominant in many regions of the world, and case numbers with Omicron subvariants BA. 1 …

[HTML][HTML] Clinical characteristics and outcomes among adults hospitalized with laboratory-confirmed SARS-CoV-2 infection during periods of B. 1.617. 2 (Delta) and B …

ME Modes - MMWR. Morbidity and mortality weekly report, 2022 - cdc.gov
Among adults hospitalized with SARS-CoV-2 infection during Omicron predominance,
COVID-19 vaccination, including with a booster dose, was associated with lower likelihood …

Impact of vaccination on the COVID-19 pandemic in US states

X Chen, H Huang, J Ju, R Sun, J Zhang - Scientific reports, 2022 - nature.com
Governments worldwide are implementing mass vaccination programs in an effort to end the
novel coronavirus (COVID-19) pandemic. Here, we evaluated the effectiveness of the …