Formulation and quality control of orally disintegrating tablets (ODTs): recent advances and perspectives

MP Ghourichay, SH Kiaie, A Nokhodchi… - BioMed Research …, 2021 - Wiley Online Library
Orally disintegrating tablets (ODTs) rapidly disintegrate or dissolve in the oral cavity without
using water. Demand for ODTs has increased, and the field has overgrown in the …

Direct compaction: An update of materials, trouble-shooting, and application

Z Li, LJ Zhao, X Lin, L Shen, Y Feng - International Journal of …, 2017 - Elsevier
Direct compaction (DC) is the preferred choice for tablet manufacturing; however, only less
than 20% of active pharmaceutical ingredients could be compacted via DC as its high …

Tailoring of rosuvastatin calcium and atenolol bilayer tablets for the management of hyperlipidemia associated with hypertension: a preclinical study

MMA Elsayed, MO Aboelez, MS Mohamed… - Pharmaceutics, 2022 - mdpi.com
Hyperlipidemia is still the leading cause of heart disease in patients with hypertension. The
purpose of this study is to make rosuvastatin calcium (ROS) and atenolol (AT) bilayer tablets …

Sodium Starch Glycolate (SSG) from Sago Starch (Metroxylon sago) as a Superdisintegrant: Synthesis and Characterization

ON Putra, I Musfiroh, S Elisa, M Musa, EHK Ikram… - Molecules, 2023 - mdpi.com
The characteristics of sago starch exhibit remarkable resemblances to those of cassava,
potato, and maize starches. This review intends to discuss and summarize the synthesis and …

Application of Biomaterials in the Development of Hydrogel-Forming Microneedles Integrated with a Cyclodextrin Drug Reservoir for Improved Pharmacokinetic …

CK Enggi, S Sulistiawati, A Himawan… - ACS Biomaterials …, 2024 - ACS Publications
Telmisartan (TEL) is a promising antihypertensive agent among other angiotensin receptor
blockers. However, its oral application is limited by its poor water solubility. This study …

Development and Evaluation of Cannabidiol Orodispersible Tablets Using a 23-Factorial Design

RA Vlad, P Antonoaea, N Todoran, EM Rédai, M Bîrsan… - Pharmaceutics, 2022 - mdpi.com
Orodispersible tablets (ODTs) are pharmaceutical formulations used to obtain fast
therapeutic effects, usually recommended for geriatric and pediatric patients due to their …

Design and characterization of intra-oral fast dissolving tablets containing diacerein-solid dispersion

A Hasan, M Abd Elghany, S Sabry - Journal of Applied …, 2020 - japsonline.com
Diacerein (Diacetylrhein, DCN) is anthraquinone derivatives used in the curing of
osteoarthritis, but its usage is restricted due to its very poor solubility and wettability which …

Acrylamide grafted neem (Azadirachta indica) gum polymer: Screening and exploration as a drug release retardant for tablet formulation

DA Bhagwat, VR Kolekar, SJ Nadaf, PB Choudhari… - Carbohydrate …, 2020 - Elsevier
The study was initiated with the intent to synthesize acrylamide grafted neem gum polymer
(AAm-g-NG), and screen its drug release retardation ability both in vitro and in vivo. Different …

Exploitation of design-of-experiment approach for design and optimization of fast-disintegrating tablets for sublingual delivery of sildenafil citrate with enhanced …

AS AlAli, MF Aldawsari, A Alalaiwe, BK Almutairy… - Pharmaceutics, 2021 - mdpi.com
Sildenafil citrate undergoes first-pass metabolism, resulting in poor oral bioavailability at 25–
41% of the administered dose. This study aimed to design and optimize fast-disintegrating …

Targeted Nano-Delivery of Flutamide with polymeric and lipid nanoparticles

A Ghaemi, A Khanizadeh, M Pourmadadi… - European Polymer …, 2024 - Elsevier
This comprehensive review analysis of the progress and modification of intelligent delivery
methods employed for the administration of Flutamide (FLT). Flutamide is given to treat and …