Key considerations during the transition from the acute phase of the COVID-19 pandemic: a narrative review
P Rzymski, M Pokorska-Śpiewak, T Jackowska… - Vaccines, 2023 - mdpi.com
The COVID-19 pandemic has been met with an unprecedented response from the scientific
community, leading to the development, investigation, and authorization of vaccines and …
community, leading to the development, investigation, and authorization of vaccines and …
[HTML][HTML] From emergence to endemicity: a comprehensive review of COVID-19
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), later renamed coronavirus
disease 2019 (COVID-19), was first identified in Wuhan, China, in early December 2019 …
disease 2019 (COVID-19), was first identified in Wuhan, China, in early December 2019 …
[HTML][HTML] a rapid global increase in COVID-19 is due to the emergence of the EG. 5 (Eris) subvariant of omicron SARS-CoV-2
DV Parums - … science monitor: international medical journal of …, 2023 - ncbi.nlm.nih.gov
A new variant of SARS-CoV-2 has currently achieved global domination. EG. 5 (Eris) was
first reported by the World Health Organization (WHO) on February 17, 2023, and …
first reported by the World Health Organization (WHO) on February 17, 2023, and …
[HTML][HTML] AlphaFold2 Modeling and Molecular Dynamics Simulations of the Conformational Ensembles for the SARS-CoV-2 Spike Omicron JN. 1, KP. 2 and KP. 3 …
N Raisinghani, M Alshahrani, G Gupta, G Verkhivker - Viruses, 2024 - mdpi.com
The most recent wave of SARS-CoV-2 Omicron variants descending from BA. 2 and BA.
2.86 exhibited improved viral growth and fitness due to convergent evolution of functional …
2.86 exhibited improved viral growth and fitness due to convergent evolution of functional …
Balancing functional tradeoffs between protein stability and ACE2 binding in the SARS-CoV-2 omicron BA. 2, BA. 2.75 and XBB lineages: dynamics-based network …
G Verkhivker, M Alshahrani, G Gupta - Viruses, 2023 - mdpi.com
Evolutionary and functional studies suggested that the emergence of the Omicron variants
can be determined by multiple fitness trade-offs including the immune escape, binding …
can be determined by multiple fitness trade-offs including the immune escape, binding …
A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron …
J Pérez-Vargas, LJ Worrall, AD Olmstead… - Emerging microbes & …, 2023 - Taylor & Francis
Antivirals with broad coronavirus activity are important for treating high-risk individuals
exposed to the constantly evolving SARS-CoV-2 variants of concern (VOCs) as well as …
exposed to the constantly evolving SARS-CoV-2 variants of concern (VOCs) as well as …
Markov State Models and Perturbation-Based Approaches Reveal Distinct Dynamic Signatures and Hidden Allosteric Pockets in the Emerging SARS-Cov-2 Spike …
The new generation of SARS-CoV-2 Omicron variants displayed a significant growth
advantage and increased viral fitness by acquiring convergent mutations, suggesting that …
advantage and increased viral fitness by acquiring convergent mutations, suggesting that …
ACE2 receptor polymorphism in humans and animals increases the risk of the emergence of SARS-CoV-2 variants during repeated intra-and inter-species host …
Like other coronaviruses, SARS-CoV-2 has ability to spread through human-to-human
transmission and to circulate from humans to animals and from animals to humans. A high …
transmission and to circulate from humans to animals and from animals to humans. A high …
Molecular in-depth on the epidemiological expansion of SARS-CoV-2 XBB. 1.5
Since the beginning of the pandemic, the generation of new variants periodically recurs. The
XBB. 1.5 SARS-CoV-2 variant is one of the most recent. This research was aimed at …
XBB. 1.5 SARS-CoV-2 variant is one of the most recent. This research was aimed at …
Breakthrough infection elicits hypermutated IGHV3-53/3-66 public antibodies with broad and potent neutralizing activity against SARS-CoV-2 variants including the …
L Li, X Chen, Z Wang, Y Li, C Wang, L Jiang… - PLoS …, 2023 - journals.plos.org
The rapid emergence of SARS-CoV-2 variants of concern (VOCs) calls for efforts to study
broadly neutralizing antibodies elicited by infection or vaccination so as to inform the …
broadly neutralizing antibodies elicited by infection or vaccination so as to inform the …