Synthesis and Evaluation of Quinazolin‐4(3H)‐one Derivatives as Multitarget Metabolic Enzyme Inhibitors: A Biochemistry‐Oriented Drug Design
In this study, imines bearing quinazolin‐4 (3H)‐one were synthesized and their inhibitory
properties were investigated against some metabolic enzymes including …
properties were investigated against some metabolic enzymes including …
Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular docking studies of new imidazolyl hydrazone derivatives
A new series of imidazolyl hydrazone derivatives IA (1-12) were prepared from a
condensation reaction between indoline-2, 3-dione (isatin) and 2 …
condensation reaction between indoline-2, 3-dione (isatin) and 2 …
Design, synthesis, characterization, crystal structure, in silico studies, and inhibitory properties of the PEPPSI type Pd (II) NHC complexes bearing chloro/fluorobenzyl …
This work contains synthesis, characterization, crystal structure, and biological activity of a
new series of the PEPPSI type Pd (II) NHC complexes [(NHC) Pd (II)(3-Cl-py)]. NMR, FTIR …
new series of the PEPPSI type Pd (II) NHC complexes [(NHC) Pd (II)(3-Cl-py)]. NMR, FTIR …
Synthesis, characterization, bioactivity impacts of new anthranilic acid hydrazones containing aryl sulfonate moiety as fenamate isosteres
In this study, it was planned to synthesize new members of fenamate isosteres and
investigate its effect on some metabolic enzymes such as Acetylcholinesterase …
investigate its effect on some metabolic enzymes such as Acetylcholinesterase …
Synthesis, spectroscopic characterization, antibacterial activity, and computational studies of novel pyridazinone derivatives
In this work, a novel series of pyridazinone derivatives (3–17) were synthesized and
characterized by NMR (1H and 13C), FT-IR spectroscopies, and ESI-MS methods. All …
characterized by NMR (1H and 13C), FT-IR spectroscopies, and ESI-MS methods. All …
Design, synthesis, characterization and biological activities of novel S‐(Acyloxy) butyl‐N, N‐diethyldithiocarbamate compounds
A Karimov, P Taslimi, A Orujova… - …, 2023 - Wiley Online Library
In this study, S‐(Acyloxy) butyl‐N, N‐Diethyldithiocarbamate compounds (P1‐P7) were
synthesized by s‐alkylation of N, N‐diethyldithiocarbamate sodium trihydrate with 4 …
synthesized by s‐alkylation of N, N‐diethyldithiocarbamate sodium trihydrate with 4 …
[HTML][HTML] Reinvigorate the synthesis, spectroscopic findings, SEM morphology investigation, and antimicrobial silhouette of contemporary Salen ligands: a …
This article has serendipitously synthesized three trendy Salen ligands (H 2 L 1/H 2 L 2/H 2
L 3) prepared from Salicylaldehyde/ortho-vanillin and the corresponding diamines …
L 3) prepared from Salicylaldehyde/ortho-vanillin and the corresponding diamines …
[PDF][PDF] Could Momordica charantia Be effective in the treatment of COVID19?
One of the deadliest diseases is the SARS-CoV-2 virus, today. The rate of spread of this
virus is very high. Momordica Charantia extracts studied for this virus. The inhibitory …
virus is very high. Momordica Charantia extracts studied for this virus. The inhibitory …
Synthesis, Biological Properties, and Molecular Docking Study of Novel 1, 2, 3-Triazole-8-quinolinol Hybrids
M El Faydy, L Lakhrissi, N Dahaieh, K Ounine… - ACS …, 2024 - ACS Publications
A new series of 1, 2, 3-triazole-8-quinolinol hybrids were synthesized in good yields using
monosubstituted acetonitriles and 5-azidomethyl-8-quinolinol as the starting reagents via a …
monosubstituted acetonitriles and 5-azidomethyl-8-quinolinol as the starting reagents via a …
Exploring the phytochemical profile and therapeutic investigations on Moringa concanensis Nimmo pod husk extracts: An integrated in vitro and in silico approach
The present study aimed to determine the chemical profiling, antidiabetic, antioxidant, and
antibacterial activity of Moringa concanensis pod husk (MCPH) by in vitro and in silico …
antibacterial activity of Moringa concanensis pod husk (MCPH) by in vitro and in silico …