Gammaherpesviruses are an important class of oncogenic pathogens that are exquisitely
evolved to their respective hosts. As such, the human gammaherpesviruses Epstein-Barr …

Viruses infect all kingdoms of life; their genomes vary from DNA to RNA and in size from 2kB
to 1 MB or more. Viruses frequently employ disordered proteins, that is, protein products of …

Compelling evidences have revealed the emerging role of ferroptosis in the
pathophysiological process of acute lung injury (ALI), but its modulation is not clear. Here …

The genome guardian p53 functions as a transcription factor that senses numerous cellular
stresses and orchestrates the corresponding transcriptional events involved in determining …

Although it is well-established that p53-mediated tumor suppression mainly acts through its
ability in transcriptional regulation, the molecular mechanisms of this regulation are not …

Lymphomas are among the most common cancers in people with HIV (PWH). The
lymphoma subtypes and pathogenesis of lymphoma in PWH are different from the …

Kaposi sarcoma-associated herpesvirus (KSHV), or human herpesvirus-8, is an oncogenic
herpesvirus. Its latency-associated nuclear antigen (LANA) is essential for the persistence of …

The humoral antibody response against Kaposi sarcoma-associated herpesvirus (KSHV) in
infected individuals has been characterized demonstrating the latency-associated nuclear …

The ability to modulate host cell cycle progression is a requirement of many human viruses
in order to facilitate their replication and propagation. Nuclear-replicating DNA viruses …

Gammaherpesviruses are DNA tumor viruses that establish lifelong latent infections in
lymphocytes. For viruses such as Epstein-Barr virus and murine gammaherpesvirus 68, this …