BACKGROUND Mucositis is a highly significant, and sometimes dose‐limiting, toxicity of
cancer therapy. The goal of this systematic review was to update the Multinational …

Approximately 50% of all patients with cancer receive radiation therapy at some point during
the course of their treatment, and the majority of these patients are treated with curative …

Reactive oxygen species (ROS) are highly reactive molecules that arise from a number of
cellular sources, including oxidative metabolism in mitochondria. At low levels they can be …

Purpose Tobacco smoking is associated with oropharynx cancer survival, but to what extent
cancer progression or death increases with increasing tobacco exposure is unknown …

Radiation is used in the treatment of a broad range of malignancies. Exposure of normal
tissue to radiation may result in both acute and chronic toxicities that can result in an inability …

Despite nearly two decades of research investigating the use of dietary antioxidant
supplementation during conventional chemotherapy and radiation therapy, controversy …

Oxidative stress is a key component in carcinogenesis. Although radiation produces reactive
oxygen species, some anticancer agents such as alkylating agents, platinum and antitumor …

Aberrant epigenetic modifications are described in an increasing number of pathological
conditions, including neurodegenerative diseases, cardiovascular diseases, diabetes …

Nutritional supplements are widely used among patients with cancer who perceive them to
be anticancer and antitoxicity agents. Large-scale, randomized cancer prevention trials have …

Only two radioprotective compounds, amifostine and palifermin, currently have the US FDA
approval for use in radiation therapy. However, several agents have been reported that …