A comprehensive review on medicinal plants as antimicrobial therapeutics: potential avenues of biocompatible drug discovery

U Anand, N Jacobo-Herrera, A Altemimi, N Lakhssassi - Metabolites, 2019 - mdpi.com
The war on multidrug resistance (MDR) has resulted in the greatest loss to the world's
economy. Antibiotics, the bedrock, and wonder drug of the 20th century have played a …

[HTML][HTML] Development of botanicals to combat antibiotic resistance

PD Gupta, TJ Birdi - Journal of Ayurveda and integrative medicine, 2017 - Elsevier
The discovery of antibiotics in the previous century lead to reduction in mortality and
morbidity due to infectious diseases but their inappropriate and irrational use has resulted in …

Plant secondary metabolites in the battle of drugs and drug-resistant bacteria: new heroes or worse clones of antibiotics?

CL Gorlenko, HY Kiselev, EV Budanova… - Antibiotics, 2020 - mdpi.com
Infectious diseases that are caused by bacteria are an important cause of mortality and
morbidity in all regions of the world. Bacterial drug resistance has grown in the last decades …

Flaxseed lignans as important dietary polyphenols for cancer prevention and treatment: Chemistry, pharmacokinetics, and molecular targets

SF De Silva, J Alcorn - Pharmaceuticals, 2019 - mdpi.com
Cancer causes considerable morbidity and mortality across the world. Socioeconomic,
environmental, and lifestyle factors contribute to the increasing cancer prevalence …

Recent approaches for downplaying antibiotic resistance: molecular mechanisms

S Ahmed, MZ Ahmed, S Rafique… - BioMed Research …, 2023 - Wiley Online Library
Antimicrobial resistance (AMR) is a ubiquitous public health menace. AMR emergence
causes complications in treating infections contributing to an upsurge in the mortality rate …

Drug bioavailability enhancing agents of natural origin (bioenhancers) that modulate drug membrane permeation and pre-systemic metabolism

B Peterson, M Weyers, JH Steenekamp, JD Steyn… - Pharmaceutics, 2019 - mdpi.com
Many new chemical entities are discovered with high therapeutic potential, however, many
of these compounds exhibit unfavorable pharmacokinetic properties due to poor solubility …

The multi-faceted potential of plant-derived metabolites as antimicrobial agents against multidrug-resistant pathogens

J Shin, VS Prabhakaran, K Kim - Microbial pathogenesis, 2018 - Elsevier
Multidrug-resistant (MDR) pathogens are currently causing serious problems globally in the
medical setting. Improper and extensive usage of antibiotics results in a selective pressure …

A recent review on bio-availability enhancement of poorly water-soluble drugs by using bioenhancer and nanoparticulate drug delivery system

M Kumar, D Kumar, S Kumar, A Kumar… - Current …, 2022 - ingentaconnect.com
Background: Intravenous route of drug administration has maximum bioavailability, which
shows 100% of the drug reaches blood circulation, whereas the oral administration of drugs …

Induction of apoptosis by pinostrobin in human cervical cancer cells: Possible mechanism of action

A Jaudan, S Sharma, SNA Malek, A Dixit - PLoS One, 2018 - journals.plos.org
Pinostrobin (PN) is a naturally occurring dietary bioflavonoid, found in various medicinal
herbs/plants. Though anti-cancer potential of many such similar constituents has been …

[HTML][HTML] Chemotherapeutic potential of cow urine: A review

GK Randhawa, R Sharma - Journal of intercultural …, 2015 - ncbi.nlm.nih.gov
In the grim scenario where presently about 70% of pathogenic bacteria are resistant to at
least one of the drugs for the treatment, cue is to be taken from traditional/indigenous …