An adrenal incidentaloma is now established as a common endocrine diagnosis that
requires a multidisciplinary approach for effective management. The majority of patients can …

Primary aldosteronism is a common cause of hypertension and is a risk factor for
cardiovascular and renal morbidity and mortality, via mechanisms mediated by both …

Objective: To develop clinical practice guidelines for the management of patients with
primary aldosteronism. Participants: The Task Force included a chair, selected by the …

Primary aldosteronism (PA), the most common form of secondary hypertension, can be
either surgically cured or treated with targeted pharmacotherapy. PA is frequently …

Primary aldosteronism is characterized by aldosterone secretion that is independent of renin
and angiotensin II and sodium status. The deleterious effects of primary aldosteronism are …

Primary aldosteronism is the most prevalent form of secondary hypertension. To explore
molecular mechanisms of autonomous aldosterone secretion, we performed exome …

Primary aldosteronism (PA) represents the most common cause of secondary hypertension,
but little is known regarding its adrenal cellular origins. Recently, aldosterone-producing cell …

Most aldosterone-producing adenomas (APAs) have gain-of-function somatic mutations of
ion channels or transporters. However, their frequency in aldosterone-producing cell …

Aldosterone-producing adenoma (APA) cause primary aldosteronism—the most frequent
form of secondary hypertension. Somatic mutations in genes coding for ion channels and …

Context: Due to selection biases and inadequate statistical power, individual studies may fail
to identify the clinical features of patients with an aldosterone-producing adenoma (APA) …