RNA-binding protein (RBP) has a highly dynamic spatiotemporal regulation process and
important biological functions. They are critical to maintain the transcriptome through post …

RNA-binding proteins (RBPs) are key players in post-transcriptional events. The
combination of versatility of their RNA-binding domains with structural flexibility enables …

Simple Summary RNA-binding proteins (RBPs) play central roles in regulating
posttranscriptional expression of genes. Many of them are known to be deregulated in a …

Alternative splicing provides a major mechanism to generate protein diversity. Increasing
evidence suggests a link of dysregulation of splicing associated with cancer. Genome-wide …

The number of factors known to participate in the DNA damage response (DDR) has
expanded considerably in recent years to include splicing and alternative splicing factors …

Ovarian cancer (OVCA) is the most lethal gynecological cancer, due predominantly to late
presentation, high recurrence rate and common chemoresistance development. The …

Background Skeletal muscles express a highly specialized proteome that allows the
metabolism of energy sources to mediate myofiber contraction. This muscle-specific …

Purpose: The BIM deletion polymorphism is associated with apoptosis resistance to EGFR
tyrosine kinase inhibitors (EGFR-TKI), such as gefitinib and erlotinib, in non–small cell lung …

Eukaryotic gene expression is intricately regulated at multiple levels. The protein‐coding
genes are first transcribed as pre‐mRNAs in the nucleus and undergo a series of RNA …

The Tumor suppressor SMAR1 (scaffold matrix attachment region binding protein 1) has a
crucial role in maintaining genomic stability, cell cycle progression and apoptosis. Our …