Advances in the chemical and biological diversity of heterocyclic systems incorporating pyrimido [1, 6-a] pyrimidine and pyrimido [1, 6-c] pyrimidine scaffolds
Heterocycles incorporating a pyrimidopyrimidine scaffold have aroused great interest from
researchers in the field of medical chemistry because of their privileged biological activities; …
researchers in the field of medical chemistry because of their privileged biological activities; …
Synthesis and QSAR studies of pyrimido [4, 5-d] pyrimidine-2, 5-dione derivatives as potential antimicrobial agents
P Sharma, N Rane, VK Gurram - Bioorganic & medicinal chemistry letters, 2004 - Elsevier
A number of pyrimido [4, 5-d] pyrimidine-2, 5-dione derivatives were synthesized and
screened for antibacterial and antifungal activities. All the synthesized compounds showed …
screened for antibacterial and antifungal activities. All the synthesized compounds showed …
Bicyclic 6+ 6 systems: the chemistry of pyrimido [4, 5-d] pyrimidines and pyrimido [5, 4-d] pyrimidines
The present study provides an overview of the chemistry and biological significance of
pyrimido [4, 5-d] pyrimidine and pyrimido [5, 4-d] pyrimidine analogs as types of bicyclic [6+ …
pyrimido [4, 5-d] pyrimidine and pyrimido [5, 4-d] pyrimidine analogs as types of bicyclic [6+ …
One-pot synthesis and antibacterial activities of pyrazolo [4′, 3′: 5, 6] pyrido [2, 3-d] pyrimidine-dione derivatives
A one-pot and efficient method for the synthesis of pyrazolo [4′, 3′: 5, 6] pyrido [2, 3-d]
pyrimidine-dione derivatives by condensation reaction of barbituric acids, 1H-pyrazol-5 …
pyrimidine-dione derivatives by condensation reaction of barbituric acids, 1H-pyrazol-5 …
A novel and efficient synthesis of pyrimido [4, 5-d] pyrimidine-2, 4, 7-trione and pyrido [2, 3-d: 6, 5-d] dipyrimidine-2, 4, 6, 8-tetrone derivatives
An efficient and direct procedure for the synthesis of pyrimido [4, 5-d] pyrimidine-2, 4, 7-
trione derivatives has been described under microwave-assisted conditions. Reaction of 6 …
trione derivatives has been described under microwave-assisted conditions. Reaction of 6 …
A Cascade Reaction with Iminium Ion Isomerization as the Key Step Leading to Tetrahydropyrimido[4,5-d]pyrimidines
L Zheng, F Yang, Q Dang, X Bai - Organic Letters, 2008 - ACS Publications
A novel cascade reaction of aminopyrimidines 1 with N-alkyl amino acids or analogues was
investigated. The keys to this cascade are the isomerization of an iminium ion formed …
investigated. The keys to this cascade are the isomerization of an iminium ion formed …
A novel reaction of 6-amino-uracils and isatins
A novel reaction of 6-amino-uracils and isatins - ScienceDirect Skip to main contentSkip to
article Elsevier logo Journals & Books Search RegisterSign in View PDF Download full issue …
article Elsevier logo Journals & Books Search RegisterSign in View PDF Download full issue …
Switchable selectivity in multicomponent heterocyclizations of acetoacetamides, aldehydes, and 3-amino-1, 2, 4-triazoles/5-aminopyrazoles
EA Muravyova, SM Desenko, RV Rudenko… - Tetrahedron, 2011 - Elsevier
Multicomponent heterocyclizations of 3-amino-1, 2, 4-triazoles/5-aminopyrazoles with
acetoacetamides and aromatic aldehydes were studied in detail using conventional thermal …
acetoacetamides and aromatic aldehydes were studied in detail using conventional thermal …
Recent developments towards the synthesis of pyrimidopyrimidine and purine derivatives
P Debnath - ChemistrySelect, 2023 - Wiley Online Library
Fused pyrimidines scaffolds such as pyrimidopyrimidines, purines and xanthines are
important structural motifs found in various natural products and drug molecules. They are …
important structural motifs found in various natural products and drug molecules. They are …
Simple Three-Component Method for the Synthesis of Spiroindeno[1,2-b]pyrido[2,3-d]pyrimidine-5,3′-indolines
G Imani Shakibaei, A Feiz… - ACS combinatorial …, 2011 - ACS Publications
An efficient, simple, and catalyst-free synthesis of spiroindeno [1, 2-b] pyrido [2, 3-d]
pyrimidine-5, 3′-indolines and spiroacenaphthylene-1, 4′-indeno-1, 5′-pyrido [2, 3-d] …
pyrimidine-5, 3′-indolines and spiroacenaphthylene-1, 4′-indeno-1, 5′-pyrido [2, 3-d] …