[HTML][HTML] Nanopore sequencing technology, bioinformatics and applications
Rapid advances in nanopore technologies for sequencing single long DNA and RNA
molecules have led to substantial improvements in accuracy, read length and throughput …
molecules have led to substantial improvements in accuracy, read length and throughput …
Artificial intelligence in molecular medicine
Artificial Intelligence in Molecular Medicine | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …
content The New England Journal of Medicine homepage Advanced Search SEARCH …
Long-read human genome sequencing and its applications
Over the past decade, long-read, single-molecule DNA sequencing technologies have
emerged as powerful players in genomics. With the ability to generate reads tens to …
emerged as powerful players in genomics. With the ability to generate reads tens to …
Opportunities and challenges in long-read sequencing data analysis
Long-read technologies are overcoming early limitations in accuracy and throughput,
broadening their application domains in genomics. Dedicated analysis tools that take into …
broadening their application domains in genomics. Dedicated analysis tools that take into …
DNA methylation cancer biomarkers: translation to the clinic
Carcinogenesis is accompanied by widespread DNA methylation changes within the cell.
These changes are characterized by a globally hypomethylated genome with focal …
These changes are characterized by a globally hypomethylated genome with focal …
DNA methylation-calling tools for Oxford Nanopore sequencing: a survey and human epigenome-wide evaluation
Background Nanopore long-read sequencing technology greatly expands the capacity of
long-range, single-molecule DNA-modification detection. A growing number of analytical …
long-range, single-molecule DNA-modification detection. A growing number of analytical …
[HTML][HTML] Nanopore sequencing and its application to the study of microbial communities
L Ciuffreda, H Rodríguez-Pérez, C Flores - Computational and structural …, 2021 - Elsevier
Since its introduction, nanopore sequencing has enhanced our ability to study complex
microbial samples through the possibility to sequence long reads in real time using …
microbial samples through the possibility to sequence long reads in real time using …
Applications of long-read sequencing to Mendelian genetics
Advances in clinical genetic testing, including the introduction of exome sequencing, have
uncovered the molecular etiology for many rare and previously unsolved genetic disorders …
uncovered the molecular etiology for many rare and previously unsolved genetic disorders …
Detection of DNA base modifications by deep recurrent neural network on Oxford Nanopore sequencing data
DNA base modifications, such as C5-methylcytosine (5mC) and N6-methyldeoxyadenosine
(6mA), are important types of epigenetic regulations. Short-read bisulfite sequencing and …
(6mA), are important types of epigenetic regulations. Short-read bisulfite sequencing and …
Modern epigenetics methods in biological research
Y Li - Methods, 2021 - Elsevier
The definition of epigenetics refers that molecular modifications on DNA that can regulate
gene activity are independent of DNA sequence and mitotically stable. Notably, epigenetics …
gene activity are independent of DNA sequence and mitotically stable. Notably, epigenetics …